Author | Grimaldi Junior, Gabriel | |
Author | Tesh, Robert B. | |
Access date | 2024-03-21T14:06:04Z | |
Available date | 2024-03-21T14:06:04Z | |
Document date | 1993 | |
Citation | GRIMALDI JUNIOR, Gabriel; TESH, Robert B. Leishmaniases of the new world: current concepts and implications for future research. Clinical Microbiology Reviews, v. 6, n. 3, p. 230-250, July 1993. | |
ISSN | 0893-8512 | |
URI | https://www.arca.fiocruz.br/handle/icict/63154 | |
Sponsorship | National Institutes of Health (AI-21049 and AI-28528). | |
Sponsorship | The MacArthur Foundation (Molecular Parasitology and Vector Biology Programs). | |
Sponsorship | The Brazilian National Council of Scientific Development and Technology(CNPq). | |
Language | eng | en_US |
Publisher | American Society for Microbiology | en_US |
Rights | open access | |
Title | Leishmaniases of the new world: current concepts and implications for future research | en_US |
Type | Article | |
DOI | 10.1128/cmr.6.3.230 | |
Abstract | Recent epidemiologic studies indicate that leishmaniasis in the Americas is far more abundant and of greater public health importance than was previously recognized. The disease in the New World is caused by a number of different parasite species that are capable of producing a wide variety of clinical manifestations. The outcome of leishmanial infection in humans is largely dependent on the immune responsiveness of the host and the virulence of the infecting parasite strain. This article reviews current concepts of the clinical forms, immunology, pathology, laboratory diagnosis, and treatment of the disease as well as aspects of its epidemiology and control. Recommendations for future research on the disease and its control are made. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil. | |
Affilliation | Yale University. School of Medicine. Department of Epidemiology and Public Health. New Haven, CT, USA. | |
Subject | Leishmaniasis | en_US |
Subject | Americas | en_US |
Subject | New world | en_US |
Subject | Leishmanial infection | en_US |
Subject | Clinical forms | en_US |
Subject | Immunology | en_US |
Subject | Pathology | en_US |
Subject | Laboratory diagnosis | en_US |
Subject | Treatment | en_US |
Subject | Epidemiology | en_US |
e-ISSN | 1098-6618 | |