| Author | Silva, Kayser Rogerio Oliveira | |
| Author | Ferreira, Rayane Cupolillo | |
| Author | Coelho, Lara E. | |
| Author | Veloso, Valdiléa G. | |
| Author | Grinsztejn, Beatriz | |
| Author | Torres, Thiago S. | |
| Author | Luz, Paula M. | |
| Access date | 2024-03-22T23:51:12Z | |
| Available date | 2024-03-22T23:51:12Z | |
| Document date | 2024 | |
| Citation | SILVA, Kayser Rogerio Oliveira et al. Knowledge of HIV transmission, prevention strategies and U = U among adult sexual and gender minorities in Brazil. Journal of the International AIDS Society, v. 27, n. 2, p. 1-13, Feb. 2024. | en_US |
| ISSN | 1758-2652 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/63185 | |
| Sponsorship | PML was supported by Fundação Oswaldo Cruz: INOVA. TST was supported by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)—Finance Code 001, CNPq,Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro #E-26/201.133/2021 and #E-26/201.270/2022 and #E-26/211.577/2021, Conselho Nacional de Desenvolvimento Científico e Tecnológico and #311871/2021-6 and #316401/2021-8 and #402916/2021-2. | en_US |
| Language | eng | en_US |
| Publisher | BioMed Central | en_US |
| Rights | open access | en_US |
| Title | Knowledge of HIV transmission, prevention strategies and U = U among adult sexual and gender minorities in Brazil | en_US |
| Type | Article | en_US |
| DOI | 10.1002/jia2.26220 | |
| Abstract | Introduction: Although strong scientific evidence of the efficacy and effectiveness of treatment-as-prevention (TasP) is available, full endorsement of the "Undetectable = Untransmittable" (U = U) and "zero-risk" messages could be improved. Increasing knowledge about HIV transmission, prevention and treatment is a critical component of care efforts. The study assessed knowledge of HIV transmission and prevention strategies, and the perceived accuracy of the slogan U = U among sexual and gender minorities (SGM) in Brazil. Methods: Cross-sectional web-based survey targeting adult SGM living in Brazil (2021-2022) recruited on social media and dating apps. We used the 12-item HIV Knowledge Assessment (HIV-KA) questionnaire to assess HIV knowledge, three items of which address pre-exposure prophylaxis (PrEP), post-exposure prophylaxis and TasP. Perceived accuracy of the U = U slogan was assessed with the question: "With regards to HIV-positive individuals transmitting HIV through sexual contact, how accurate do you believe the slogan U = U is?". We a priori grouped the study population into three mutually exclusive groups: people living with HIV (PLHIV), HIV negative and HIV unknown. We used logistic regression models to assess factors associated with high HIV knowledge and perception of the U = U as completely accurate. Results: Of 50,222 individuals accessing the questionnaire, 23,981 were included: 5071 (21.0%) PLHIV, 17,257 (71.5%) HIV negative and 1653 (6.9%) HIV unknown. The proportion of participants with high knowledge was significantly higher for PLHIV and HIV negative (48.1% and 45.5%, respectively) compared to 26.1% of HIV unknown. More PLHIV perceived U = U as completely accurate (80.4%), compared to 60.0% of HIV negative and 42.9% of HIV unknown. HIV knowledge correlates with perceived accuracy of the U = U slogan across all groups. Higher HIV knowledge was associated with higher income and education regardless of HIV status. Among HIV-negative participants, PrEP awareness and use were associated with higher knowledge and accurate perception of the U = U slogan. Conclusions: Our findings show that HIV knowledge and perceived accuracy of U = U are strongly correlated, that knowledge differs according to HIV status, and that poor socio-economic is linked to poor knowledge among SGM from Brazil. Educational strategies regarding TasP, U = U and zero risk targeting socio-economically vulnerable populations are urgent in Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Subject | HIV knowledge | en_US |
| Subject | Undetectable = Untransmittable (U = U) | en_US |
| Subject | Treatment-as-prevention | en_US |
| Subject | Zero-risk | en_US |
| Subject | Sexual and gender minorities | en_US |
| Subject | Latin America | en_US |
| e-ISSN | 1758-2652 | |
| xmlui.metadata.dc.subject.ods | 04 Educação de qualidade | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
