| Autor | Coelho, Lara E. | |
| Autor | Jenkins, Cathy A. | |
| Autor | Shepherd, Bryan E. | |
| Autor | Pape, Jean W. | |
| Autor | Cordero, Fernando Mejia | |
| Autor | Padgett, Denis | |
| Autor | Ramirez, Brenda Crabtree | |
| Autor | Grinsztejn, Beatriz | |
| Autor | Althoff, Keri N. | |
| Autor | Koethe, John R. | |
| Autor | Marconi, Vincent C. | |
| Autor | Tien, Phyllis C. | |
| Autor | Willig, Amanda L. | |
| Autor | Moore, Richard D. | |
| Autor | Castilho, Jessica L. | |
| Autor | Colasanti, Jonathan | |
| Autor | Crane, Heidi M. | |
| Autor | Gill, M. John | |
| Autor | Horberg, Michael A. | |
| Autor | Mayor, Angel | |
| Autor | Silverberg, Michael J. | |
| Autor | McGowan, Catherine | |
| Autor | Rebeiro, Peter F. | |
| Data de acesso | 2024-07-12T23:47:40Z | |
| Data de disponibilização | 2024-07-12T23:47:40Z | |
| Data do publicação | 2022 | |
| Citação | COELHO, Lara E. et al. Weight gain post-ART in HIV+ Latinos/as differs in the USA, Haiti, and Latin America. Lancet Regional Health. Americas. v. 8, p. 1-11. Apr. 2022. | en_US |
| ISSN | 2667-193X | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/64967 | |
| Descrição | On behalf of the North American AIDS Collaboration on Research and Design (NA-ACCORD) and the Caribbean, Central and South America network for HIV epidemiology (CCASAnet) of the International epidemiology Databases to Evaluate AIDS (IeDEA). | en_US |
| Fomento | This work was supported by the NIH-funded Caribbean, Central and South America network for HIV epidemiology (CCASAnet, U01AI069923) and the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD, U01AI069918), member cohorts of the International Epidemiologic Databases to Evaluate AIDS (leDEA). These awards are funded by the following institutes: Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD), National Cancer Institute (NCI), National Institute Of Allergy And Infectious Diseases (NIAID), National Institute Of Mental Health (NIMH), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and the Fogarty International Center (FIC). Specific funding was provided from the Fogarty
International Center (FIC) for lead author, Lara Coelho, for the Fogarty-IeDEA Mentorship Program (FIMP). | en_US |
| Idioma | eng | en_US |
| Editor | Elsevier | en_US |
| Versão anterior | https://www.arca.fiocruz.br/handle/icict/52900 | en_US |
| Direito Autoral | open access | en_US |
| Título | Weight gain post-ART in HIV+ Latinos/as differs in the USA, Haiti, and Latin America | en_US |
| Tipo do documento | Article | en_US |
| DOI | 10.1016/j.lana.2021.100173 | |
| Resumo em Inglês | Background: An obesity epidemic has been documented among adult Latinos/as in Latin America and the United States (US); however, little is known about obesity among Latinos/as with HIV (PWH). Moreover, Latinos/as PWH in the US may have different weight trajectories than those in Latin America due to the cultural and environmental contexts. We assessed weight and body mass index (BMI) trajectories among PWH initiating antiretroviral therapy (ART) across 5 countries in Latin America and the Caribbean and the US. Methods: ART-naÿve PWH ≥18 years old, enrolled in Brazil, Honduras, Mexico, Peru, and Haiti (sites within CCA-SAnet) and the US (NA-ACCORD) starting ART between 2000 and 2017, with at least one weight measured after ART initiation were included. Participants were classified according to site/ethnicity as: Latinos/as in US, non-Latinos/as in US, Haitians, and Latinos/as in Latin America. Generalized least squares models were used to assess trends in weight and BMI. Models estimating probabilities of becoming overweight/obese (BMI ≥25 kg/m2) and of becoming obese (BMI ≥30 kg/m2) post ART initiation for males and females were fit using generalized estimating equations with a logit link and an independence working correlation structure. Findings: Among 59,207 PWH, 9% were Latinos/as from Latin America, 9% Latinos/as from the US, 68% non-Latinos/as from the US and 14% were Haitian. At ART initiation, 29% were overweight and 14% were obese. Post-ART weight and BMI increases were steeper for Latinos/as in Latin America compared with other sites/ethnicities; however, BMI at 3-years post ART remained lower compared to Latinos/as and non-Latinos/as in the US. Among females, at 3-years post ART initiation the greatest adjusted probability of obesity was found among non-Latinas in the US (15·2%) and lowest among Latinas in Latin America (8.6%). Among males, while starting with a lower BMI, Latinos in Latin America had the greatest adjusted probability of becoming overweight or obese 3-years post-ART initiation. Interpretation: In the Americas, PWH gain substantial weight after ART initiation. Despite environmental and cultural differences, PWH in Latin America, Haiti and Latinos and non-Latinos in the US share similar BMI trajectories on ART and high probabilities of becoming overweight and obese over time. Multicohort studies are needed to better understand the burden of other metabolic syndrome components in PWH across different countries. | en_US |
| Afiliação | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
| Afiliação | Vanderbilt University Medical Center. Department of Biostatistics. Nashville, TN, USA. | en_US |
| Afiliação | Vanderbilt University Medical Center. Department of Biostatistics. Nashville, TN, USA. | en_US |
| Afiliação | Groupe Haitien d'Etudes du Sarcome de Kaposi et des Infections Opportunistes. Port-au-Prince, Haiti. | en_US |
| Afiliação | Universidad Peruana Cayetano Heredia. Instituto de Medicina Tropical Alexander von Humboldt. Lima, Peru. | en_US |
| Afiliação | Instituto Hondureño de Seguridad Social & Hospital Escuela Universitario. Tegucigalpa, Honduras. | en_US |
| Afiliação | Salvador Zubirán National Institute of Health Sciences and Nutrition. Department of Infectious Diseases. Mexico City, Mexico. | en_US |
| Afiliação | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
| Afiliação | Johns Hopkins University. Baltimore, MD, USA. | en_US |
| Afiliação | Vanderbilt University Medical Center. Division of Infectious Diseases. Nashville, TN, USA. | en_US |
| Afiliação | Emory University School of Medicine and Rollins School of Public Health. Atlanta, GA, USA. | en_US |
| Afiliação | University of California. Department of Medicine. San Francisco, CA, USA / The Department of Veterans Affairs Medical Center. San Francisco, CA, USA. | en_US |
| Afiliação | University of Alabama at Birmingham. School of Medicine. Birmingham, AL, USA. | en_US |
| Afiliação | Johns Hopkins University. Baltimore, MD, USA. | en_US |
| Afiliação | Vanderbilt University Medical Center. Division of Infectious Diseases. Nashville, TN, USA. | en_US |
| Afiliação | Emory University School of Medicine and Rollins School of Public Health. Atlanta, GA, USA. | en_US |
| Afiliação | University of Washington. Seattle, WA, USA. | en_US |
| Afiliação | The University of Calgary. Calgary, AB, Canada. | en_US |
| Afiliação | Kaiser Permanente. Mid-Atlantic Permanente Research Institute. Rockville, MD, USA. | en_US |
| Afiliação | Universidad Central del Caribe. Retrovirus Research Center. Bayamón, Puerto Rico. | en_US |
| Afiliação | Kaiser Permanente Northern California. Oakland, CA, USA. | en_US |
| Afiliação | Vanderbilt University Medical Center. Division of Infectious Diseases. Nashville, TN, USA. | en_US |
| Afiliação | Vanderbilt University Medical Center. Department of Biostatistics. Nashville, TN, USA / Vanderbilt University Medical Center. Division of Infectious Diseases. Nashville, TN, USA. | en_US |
| Palavras-chave em inglês | Weight gain | en_US |
| Palavras-chave em inglês | Obesity | en_US |
| Palavras-chave em inglês | HIV | en_US |
| Palavras-chave em inglês | Antiretroviral | en_US |
| Palavras-chave em inglês | Latin America | en_US |
| Palavras-chave em inglês | Ethnicity | en_US |
| e-ISSN | 2667-193X | |
