| Author | Azambuja, Pedro | |
| Author | Bastos, Leonardo S. L. | |
| Author | Batista-da-Silva, Amanda A. | |
| Author | Ramos, Grazielle Viana | |
| Author | Kurtz, Pedro | |
| Author | Dias, Carolina M. C. | |
| Author | Silva, Everton P. da | |
| Author | Arouca, Luna E. | |
| Author | Soares, Jesus | |
| Author | Sejvar, James J. | |
| Author | Sigfrid, Louise | |
| Author | Ranzani, Otavio T. | |
| Author | Hamacher, Silvio | |
| Author | Bozza, Fernando A. | |
| Access date | 2024-08-20T22:56:25Z | |
| Available date | 2024-08-20T22:56:25Z | |
| Document date | 2024 | |
| Citation | AZAMBUJA, Pedro et al. Prevalence, risk factors, and impact of long COVID in a socially vulnerable community in Brazil: a prospective cohort study. Lancet Regional Health. Americas, v. 37, p. 1-11, Sept. 2024. | en_US |
| ISSN | 2667-193X | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/65455 | |
| Sponsorship | UK Foreign, Commonwealth and Development Office and Wellcome Trust Grant (222048/Z/20/Z), Fundação Oswaldo Cruz (FIOCRUZ), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), and the Centers for Disease Control and Prevention (CDC). | en_US |
| Language | eng | en_US |
| Publisher | Elsevier | en_US |
| Rights | open access | en_US |
| Title | Prevalence, risk factors, and impact of long COVID in a socially vulnerable community in Brazil: a prospective cohort study | en_US |
| Type | Article | en_US |
| DOI | 10.1016/j.lana.2024.100839 | |
| Abstract | Background: Long COVID is an emerging global public health issue. Socially vulnerable communities in low- and-middle-income countries were severely impacted by the pandemic and are underrepresented in research. This prospective study aimed to determine the prevalence of long COVID, its impact on health, and associated risk factors in one such community in Rio de Janeiro, Brazil. Methods: A total of 710 individuals aged 18 and older, with confirmed SARS-CoV-2 infection at least three months prior, were enrolled between November 25, 2021, and May 5, 2022. Participants were assessed via telephone or in person using a standardized questionnaire to evaluate their perception of recovery, symptoms, quality of life, and functional status. Findings: Twenty percent of participants did not feel fully recovered, 22% experienced new or persistent symptoms, 26% had worsened functional status, 18% had increased dyspnoea, and 32% reported a worse quality of life. Persistent symptoms included headache, cough, fatigue, muscle pain, and shortness of breath. Dyspnoea during the acute phase was the strongest independent predictor of worsening outcomes. Females and individuals with comorbidities were more likely to report worse recovery, functioning, dyspnoea, and quality of life. Interpretation: Our findings reveal a high burden of severe and persistent physical and mental health sequelae in a socially vulnerable community following COVID-19. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | D'Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | D'Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Hospital Copa Star. Rio de Janeiro, RJ, Brazil / Paulo Niemeyer State Brain Institute. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Associação de Desenvolvimento Redes da Maré. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Associação de Desenvolvimento Redes da Maré. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Associação de Desenvolvimento Redes da Maré. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Division of High-Consequence Pathogens and Pathology. National Center for Emerging and Zoonotic Infectious Diseases. Centers for Disease Control and Prevention. Atlanta, GA, USA. | en_US |
| Affilliation | Division of High-Consequence Pathogens and Pathology. National Center for Emerging and Zoonotic Infectious Diseases. Centers for Disease Control and Prevention. Atlanta, GA, USA. | en_US |
| Affilliation | University of Oxford. Pandemic Sciences Institute. Policy and Practice Research Group. ISARIC Global Support Centre. Oxford, UK. | en_US |
| Affilliation | Hospital Clínic-Universitat de Barcelona. Barcelona Institute for Global Health. ISGlobal. Barcelona, Spain / Universidade de São Paulo. Faculdade de Medicina. Hospital das Clínicas. Instituto do Coração. Divisão Pulmonar. São Paulo, SP, Brasil. | en_US |
| Affilliation | Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Clinical Research Laboratory in Intensive Medicine. Rio de Janeiro, RJ, Brazil / D'Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Universidade NOVA de Lisboa. NOVA Medical School. Comprehensive Health Research Centre. Lisbon, Portugal. | en_US |
| Subject | Long COVID | en_US |
| Subject | Post-acute COVID-19 syndrome | en_US |
| Subject | Post-covid condition | en_US |
| Subject | Social vulnerability | en_US |
| Subject | Risk factors | en_US |
| e-ISSN | 2667-193X | |
| xmlui.metadata.dc.subject.ods | 01 Erradicação da pobreza | |
