| Author | Cruvinel, Vanessa Resende Nogueira | |
| Author | Carvalho, Eneas de | |
| Author | Alves, Daiani Cristina Cilião | |
| Author | Marques, Carla Pintas | |
| Author | Bezerra, Rafael Dos Santos | |
| Author | Giovanetti, Marta | |
| Author | Sampaio, Sandra Coccuzzo | |
| Author | Elias, Maria Carolina | |
| Author | Araújo, Wildo Navegantes de | |
| Author | Haddad, Rodrigo | |
| Author | Slavov, Svetoslav Nanev | |
| Access date | 2024-09-19T14:35:41Z | |
| Available date | 2024-09-19T14:35:41Z | |
| Document date | 2024 | |
| Citation | CRUVINEL, Vanessa Resende Nogueira et al. Unveiling microbial worlds: exploring viral metagenomics among waste pickers at Latin America's largest dumpsite. Rev Inst Med Trop Sao Paulo, v. 66, p. e49-e49, 2024. doi.org/10.1590/S1678-9946202466049. | en_US |
| ISSN | 0036-4665 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/65960 | |
| Language | eng | en_US |
| Publisher | Instituto de Medicina Tropical de São Paulo | en_US |
| Rights | open access | en_US |
| Title | Unveiling microbial worlds: exploring viral metagenomics among waste pickers at Latin America's largest dumpsite. | en_US |
| Type | Article | en_US |
| Abstract | Waste pickers constitute a marginalized demographic engaged in the collection of refuse, facing considerable occupational hazards that heighten their susceptibility to contract infectious diseases. Moreover, waste pickers contend with societal stigmatization and encounter barriers to accessing healthcare services. To explore the viral profile of waste pickers potentially linked to their occupational environment, we conducted a metagenomic analysis on 120 plasma specimens sampled from individuals employed at the Cidade Estrutural dumpsite in Brasilia city, Brazil. In total, 60 blood donors served as a comparative control group. Specimens were pooled and subjected to Illumina NextSeq 2000 sequencing. Viral abundance among waste pickers revealed the presence of significant pathogens, including HIV, HCV, and Chikungunya, which were not detected in the control group. Additionally, elevated levels of anelloviruses and Human pegivirus-1 were noted, with a comparable incidence in the control group. These findings underscore the utility of metagenomics in identifying clinically relevant viral agents within underserved populations. The implications of this study extend to informing public health policies aimed at surveilling infectious diseases among individuals facing socioeconomic disparities and limited access to healthcare resources. | en_US |
| Affilliation | Universidade de Brasília. Faculdade de Ceilândia. Brasília, DF, Brazil. | en_US |
| Affilliation | Instituto Butantan. Laboratório de Bacteriologia. São Paulo, SP, Brazil. | en_US |
| Affilliation | Centro Universitário Unieuro. Brasília, DF, Brazil. | en_US |
| Affilliation | Universidade de Brasília. Faculdade de Ceilândia. Brasília, DF, Brazil. | en_US |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brazil. | en_US |
| Affilliation | Università Campus Bio-Medicio di Roma. Dipartimento di Scienze e Tecnologie per l´Uomo e l´Ambiente. Roma, Italy/Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil/Climate Amplified Diseases and Epidemics. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Instituto Butantan. Centro de Vigilância Viral e Avaliação Sorológica. São Paulo, SP, Brazil. | en_US |
| Affilliation | Instituto Butantan. Centro de Vigilância Viral e Avaliação Sorológica. São Paulo, SP, Brazil. | en_US |
| Affilliation | Universidade de Brasília. Faculdade de Ceilândia. Brasília, DF, Brazil/Universidade de Brasília. Núcleo de Medicina Tropical. Brasília, DF, Brazil. | en_US |
| Affilliation | Universidade de Brasília. Faculdade de Ceilândia. Brasília, DF, Brazil/Universidade de Brasília. Núcleo de Medicina Tropical. Brasília, DF, Brazil. | en_US |
| Affilliation | Instituto Butantan. Centro de Vigilância Viral e Avaliação Sorológica. São Paulo, SP, Brazil. | en_US |
| Subject | Waste pickers | en_US |
| Subject | Metagenomics | en_US |
| Subject | Infectious diseases | en_US |
| Subject | Viral profile | en_US |
| Subject | Surveillance | en_US |
| Subject | Brazil | en_US |
| xmlui.metadata.dc.subject.ods | 12 Consumo e produção responsáveis | |
