| Author | Baldo, Marcelo Perim | |
| Author | Zaniqueli, Divanei dos Anjos | |
| Author | Cunha, Roberto de Sá | |
| Author | Barreto, Sandhi Maria | |
| Author | Bensenor, Isabela Judith Martins | |
| Author | Lotufo, Paulo Andrade | |
| Author | Mill, José Geraldo | |
| Access date | 2024-10-07T11:40:11Z | |
| Available date | 2024-10-07T11:40:11Z | |
| Document date | 2024 | |
| Citation | BALDO, Marcelo Perim et al. Association between leisure-time physical activity and arterial stiffness in adults of the ELSA-Brasil study: a mediation analysis. Journal of Hypertension, v. 42, n. 10, p. 1711-1719, Oct. 2024. | |
| ISSN | 0263-6352 | |
| URI | https://www.arca.fiocruz.br/handle/icict/66339 | |
| Description | Produção científica do Laboratório de Educação em Ambiente e Saúde. | pt_BR |
| Sponsorship | The ELSA-Brasil study was supported by the Brazilian Ministry of Health (Department of Science and Technology) and the Ministry of Science, Technology, and Innovation (FINEP, Financiadora de Estudos e Projetos), grant nos. 01 06 0010.00, 01 06 0212.00,01 06 0300.00, 01 06 0278.00, 01 06 0115.00, and 01 06 0071.00 and CNPq (the National Council for Scientific and Technological Development). | |
| Language | eng | en_US |
| Publisher | Lippincott, Williams & Wilkins | |
| Rights | restricted access | |
| Title | Association between leisure-time physical activity and arterial stiffness in adults of the ELSA-Brasil study: a mediation analysis | en_US |
| Type | Article | |
| DOI | 10.1097/HJH.0000000000003784 | |
| Abstract | Objectives: We aimed at defining the direct and the mediated pathways for the association between leisure-time physical activity (LTPA) and carotid-to-femoral pulse wave velocity (cf-PWV), and also to identify whether these effects are influenced by sex and age. Methods: Cross-sectional data from 13 718 adults (35–74 years) were obtained at the baseline of the ELSA-Brasil study. The cf-PWV was obtained by measuring the pulse transit time and the distance traveled by the pulse between the carotid and the femoral, as well as clinical and anthropometric parameters were measured. The levels of LTPA were determined by applying the long form of the International Physical Activity Questionnaire (IPAQ). Results: Classical cardiovascular risk factors were independently associated with cf-PWV. Path analysis showed that increased levels of LTPA were directly associated with lower cf-PWV in both men and women (β: −0.123 ± 0.03 vs. 0.065 ± 0.029, P for sex = 0.165), except for diabetes. Also, the mediated effect of LTPA on SBP and DBPs, heart rate, BMI, and fasting glucose, was associated with lower cf-PWV in men and women (β: −0.113 ± 0.016 vs. −0.104 ± 0.016, P for sex = 0.692), except for diabetes. When age was tested as a moderator, the direct effect did not change significantly according to participants’ age, regardless of sex. However, the mediated effect increases in both men and women over 50 years. Conclusion: Our findings support that LTPA in adults reduces cf-PWV by acting in different ways according to age. Physical activity in older individuals improves cardiometabolic risk factors and thus mitigates the stiffening of large arteries. | en_US |
| Affilliation | Montes Claros State University. Department of Pathophysiology. Montes Claros, MG, Brasil. | |
| Affilliation | Federal University of Espírito Santo. Department of Physiological Sciences. Vitória, ES, Brasil. | |
| Affilliation | Federal University of Espírito Santo. Department of Physiological Sciences. Vitória, ES, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidade Federal de Minas Gerais. Faculty of Medicine. Empresa Brasileira de Serviços Hospitalares. Clinical Hospital. Belo Horizonte, MG, Brasil. | |
| Affilliation | University of São Paulo. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brasil. | |
| Affilliation | University of São Paulo. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brasil. | |
| Affilliation | Federal University of Espírito Santo. Department of Physiological Sciences. Vitória, ES, Brasil. | |
| Subject | Aging | en_US |
| Subject | Cardiometabolic risk factors | en_US |
| Subject | Physical activity | en_US |
| Subject | Pulse wave velocity | en_US |
| e-ISSN | 1473-5598 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
