| Author | Chibante, Fernanda Oliveira | |
| Author | Faria, Anamélia Costa | |
| Author | Ribeiro-Alves, Marcelo | |
| Author | Costa, Claudia Henrique da | |
| Author | Lopes, Agnaldo José | |
| Author | Mafort, Thiago Thomaz | |
| Author | Rufino, Rogerio | |
| Access date | 2024-10-30T01:00:54Z | |
| Available date | 2024-10-30T01:00:54Z | |
| Document date | 2024 | |
| Citation | CHIBANTE, Fernanda Oliveira et al. Questionnaire and polysomnographic evaluation of obstructive sleep apnea in a cohort of post-COVID-19 patients. Medicine, v. 103, n. 37, p. 1-6, Sept. 2024. | en_US |
| ISSN | 0025-7974 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/66790 | |
| Sponsorship | This project was supported by Rio de Janeiro State Research Foundation (FAPERJ)—n.200.311/2023. | en_US |
| Language | eng | en_US |
| Publisher | Lippincott Williams & Wilkins | en_US |
| Rights | open access | en_US |
| Title | Questionnaire and polysomnographic evaluation of obstructive sleep apnea in a cohort of post-COVID-19 patients | en_US |
| Type | Article | en_US |
| DOI | 10.1097/MD.0000000000038838 | |
| Abstract | To evaluate the efficiency of 5 screening questionnaires for obstructive sleep apnea (OSA), OSA frequency, and the association between OSA and COVID-19 severity in recent COVID-19 cases, and to compare the use of the oxygen desaturation index (ODI) as an alternative measure for the respiratory disturbance index (RDI). This open cohort study recruited patients with recent COVID-19 (within 30-180 days) diagnosed using reverse transcription polymerase chain reaction. Participants were screened for OSA using the following 5 sleep disorder questionnaires prior to undergoing type I polysomnography: the Sleep Apnea Clinical Score (SACS), Epworth Sleepiness Scale (ESS), STOP-Bang score, No-Apnea score, and Berlin questionnaire. Polysomnography revealed that 77.5% of the participants had OSA and that these patients exhibited higher COVID-19-related hospitalization (58%) than those exhibited by non-apneic patients. The Kappa coefficient showed reasonable agreement between RDI > 5/h and No-Apnea score, RDI > 15/h and Berlin questionnaire score, and Epworth Sleepiness Scale and STOP-Bang score, but only moderate agreement between RDI > 15/h and No-Apnea score. An OSA-positive No-Apnea score increased the specificity of the SACS to 100% when RDI > 5/h. The intraclass correlation coefficient showed 95.2% agreement between RDI > 5/h and ODI > 10/h. The sequential application of the No-Apnea score and SACS was the most efficient screening method for OSA, which had a moderately high incidence among the post-COVID-19 group. We demonstrated an association between OSA and COVID-19 related hospitalization and that ODI could be a simple method with good performance for diagnosing OSA in this population. Abbreviations: AHI = apnea/hypopnea, CI = confidence interval, ESS = Epworth Sleepiness Scale, NPV = negative predictive values, ODI = oxygen desaturation index, OSA = obstructive sleep apnea, PPV = positive predictive values, PSG1 = type I polysomnography, RDI = respiratory disturbance index, SACS = sleep apnea clinical score, SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2, Spo2 = peripheral oxygen saturation. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Rio de Janeiro State University. Rio de Janeiro, RJ, Brazil. | en_US |
| Subject | COVID-19 | en_US |
| Subject | Obstructive sleep apnea | en_US |
| Subject | Polysomnography | en_US |
| Subject | Post-COVID-19 syndrome | en_US |
| Subject | SARS-CoV-2 | en_US |
| Subject | Sleep disorder questionnaires | en_US |
| e-ISSN | 1536-5964 | |
