| Author | Devilliers, Julien | |
| Author | Marshall, Hollie | |
| Author | Warren, Ben | |
| Author | Kyriacou, Charalambos P. | |
| Author | Araripe, Luciana Ordunha | |
| Author | Bruno, Rafaela Vieira | |
| Author | Rosato, Ezio | |
| Author | Feuda, Roberto | |
| Access date | 2024-11-05T13:36:10Z | |
| Available date | 2024-11-05T13:36:10Z | |
| Document date | 2024 | |
| Citation | DEVILLIERS, Julien et al. Molecular correlates of swarming behaviour in Aedes aegypti males. Biology Letters, v. 20, n. 10, p. 1-8, 30 Oct. 2024. | |
| ISSN | 1744-9561 | |
| URI | https://www.arca.fiocruz.br/handle/icict/66971 | |
| Description | Produção científica do Laboratório de Biologia Molecular de Insetos. | pt_BR |
| Sponsorship | This work was funded by grant E-26/201.334/2016 (FAPERJ – Brazil) to Rafaela Vieira Bruno and by a UKRI Global Challenges Research Fund (M38PF27) to Ezio Rosato, Charalambos P. Kyriacou and Roberto Feuda. Roberto Feuda acknowledges a Royal Society University Research Fellowship (UF160226). Julien Devilliers is supported by a PhD scholarship from the College of Life Science (University of Leicester). | |
| Language | eng | en_US |
| Publisher | The Royal Society | |
| Rights | open access | |
| Title | Molecular correlates of swarming behaviour in Aedes aegypti males | en_US |
| Type | Article | |
| DOI | 10.1098/rsbl.2024.0245 | |
| Abstract | Mosquitoes are the deadliest vectors of diseases. They impose a huge health burden on human populations spreading parasites as disparate as protozoans (malaria), viruses (yellow fever and more) and nematodes (filariasis) that cause life-threatening conditions. In recent years, mating has been proposed as a putative target for population control. Mosquitoes mate mid-air, in swarms initiated by males and triggered by a combination of internal and external stimuli. As the number of females in a swarm is limited, there is intense competition among males, and they ‘retune’ their physiology for this demanding behaviour. There is limited knowledge on the ‘genetic reprogramming’ required to enable swarming. Interestingly, recent evidence indicates that the upregulation of circadian clock genes may be involved in the swarming of malaria mosquitoes of the genus Anopheles. Here, we use whole-head RNA-seq to identify gene expression changes in Aedes aegypti males that are engaged in swarming in a laboratory setting. Our results suggest that in preparation to swarming, males tend to lower some housekeeping functions while increasing remodelling of the cytoskeleton and neuronal connectivity; the transcription of circadian clock genes is unaffected. | en_US |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Affilliation | University of Leicester. Neurogenetics Group. Leicester, UK / University of Leicester. College of Life Sciences. Department of Genetics, Genomics & Cancer Sciences. Leicester, UK. | |
| Subject | Aedes aegypti | en_US |
| Subject | Swarming | en_US |
| Subject | Transcriptomics | en_US |
| Subject | Circadian clock | en_US |
| e-ISSN | 1744-957X | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 09 Indústria, inovação e infraestrutura | |
| xmlui.metadata.dc.subject.ods | 11 Cidades e comunidades sustentáveis | |
| xmlui.metadata.dc.subject.ods | 13 Ação contra a mudança global do clima | |
