| Author | Fonseca, Erica Lourenço da | |
| Author | Freitas, Fernanda dos Santos | |
| Author | Morgado, Sergio Mascarenhas | |
| Author | Souza, Rosângela Cipriano de | |
| Author | Vicente, Ana Carolina Paulo | |
| Access date | 2024-11-22T14:22:50Z | |
| Available date | 2024-11-22T14:22:50Z | |
| Document date | 2024 | |
| Citation | FONSECA, Erica Lourenço da et al. Emergence of elizabethkingia miricola in the brazilian Amazon region. Science of the Total Environment, v. 907, n. 168166, p. 1-10, 10 Jan. 2024. | |
| ISSN | 0048-9697 | |
| URI | https://www.arca.fiocruz.br/handle/icict/67223 | |
| Description | Produção científica do Laboratório de Genética Molecular de Microrganismos. | pt_BR |
| Sponsorship | This work was supported by the Oswaldo Cruz Institute and FAPERJ grants. | |
| Language | eng | en_US |
| Publisher | Elsevier | |
| Rights | restricted access | |
| Title | Emergence of elizabethkingia miricola in the brazilian Amazon region | en_US |
| Type | Article | |
| DOI | 10.1016/j.scitotenv.2023.168166 | |
| Abstract | Infectious diseases are not only a threat to humans and animals but also to an entire ecosystem if the three axis of One Health are considered. Elizabethkingia miricola is a water-borne and opportunistic pathogen frequently evolving to high morbidity and mortality outcomes. More recently, reports on E. miricola infections causing death in different anuran species are increasing. Here, we reported the emergence, in a clinical setting in Brazil (Amazon region), of an E. miricola (EM15) with an almost untreatable antibiotic resistance phenotype that was closely related to the lineage involved with anuran infections worldwide. A genomic reconstruction revealed that EM15 belonged to a cluster represented by genomes from human and animal (anurans) sources recovered from China, Europe, and the Americas from 2002 to 2021, and from the Space Station Mir condensation water. Their resistome and virulome were also in agreement with their genetic relationship since they harboured the same set of resistance and putative virulence genes. Therefore, the emergence of EM15 in a clinical setting in the Amazon region, a hotspot area of anuran diversity and home to Amerindian groups that live in close relationship with the wildlife, may represent a warning to the public and environmental health. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidade Federal do Maranhão. Centro de Ciências Biológicas e da Saúde. Departamento de Medicina. São Luís, MA, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil. | |
| Subject | Multidrug resistance | en_US |
| Subject | Virulome | en_US |
| Subject | Anuran | en_US |
| Subject | One Health | en_US |
| Subject | Genomic epidemiology | en_US |
| Subject | Elizabethkingia miricola | en_US |
| e-ISSN | 1879-1026 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 06 Água potável e saneamento | |
| xmlui.metadata.dc.subject.ods | 15 Vida terrestre | |
| xmlui.metadata.dc.subject.ods | 17 Parcerias e meios de implementação | |
