| Author | Rodrigues, Maria Carolina Peixoto | |
| Author | Adesse, Daniel Pedra | |
| Author | Vianna, Marcelo | |
| Author | Hauser-Davis, Rachel Ann | |
| Access date | 2024-12-02T17:47:49Z | |
| Available date | 2024-12-02T17:47:49Z | |
| Document date | 2025 | |
| Citation | RODRIGUES, Maria Carolina Peixoto et al. Shark-on-a-dish: elasmobranch cell cultures as a promising tool for the conservation of threatened species. Marine Pollution Bulletin, v. 210, n. 117349, p. 1-12, Jan. 2025. | |
| ISSN | 0025-326X | |
| URI | https://www.arca.fiocruz.br/handle/icict/67377 | |
| Description | Produção científica do Laboratório de Avaliação e Promoção da Saúde Ambiental. | pt_BR |
| Description | Produção científica do Laboratório de Biologia Estrutural. | pt_BR |
| Sponsorship | Rachel Ann Hauser-Davis and Daniel Pedra Adesse. would like to thank the Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ): Projetos Temáticos grant numbers E-26/010-001199/2015 and SEI-26 260003/001351/2020, for Daniel Pedra Adesse; Redes em Saúde, grant number E-26-211.570/2019, for Daniel Pedra Adesse; Apoio ao Jovem Pesquisador Fluminense com Vínculo em ICTS do Estado do RJ 2021, grant number E-26/210.300/20222, for Rachel Ann Hauser-Davis; Jovem Cientista do Nosso Estado 2021–2024 grant number E-26/201.270/202, for Rachel Ann Hauser-Davis and E-26/201.336/2021 for Daniel Pedra Adesse; Cientista do Nosso Estado 2024-2027 grant number E-26/204.304/2024 for Daniel Pedra Adesse; the Brazilian National Council of Scientific and Technological Development (productivity grant, process number 308811/2021-6). The implementation of the Projeto Pesquisa Marinha e Pesqueira is a compensatory measure established by the Conduct Adjustment Agreement under the responsibility of the PRIO company, conducted by the Federal Public Ministry-MPF/RJ. This work was also prepared with resources from the Judicial Agreement Term signed between the Federal Public Prosecutor's Office, the Public Prosecutor's Office of the State of Paraná and Petrobras, with the intervention of the Brazilian Fund for Biodiversity (Funbio) and the Chico Mendes Institute for Biodiversity Conservation (ICMBio), within the scope of the Sentence Enforcement process No. 5001337-92.2012.4.04.7008, arising from Public Civil Actions 0000041-91.2010.404.7008 (PR) and No. 200270080002601, brought by the IAP — Paraná Environmental Institute and by the MPPR and MPF, respectively against Petróleo Brasileiro S/A — Petrobrás. Daniel Pedra Adesse is also supported by a special grant from a Federal Deputy Fund (Marcelo Freixo 2022-2023), award number IOC-008-FIO-23 and from the INOVA IOC “Neuro-Infections Network” (IOC-026-FIO-21). D.A. was awarded a Tripartite Grant (Fiocruz-USP-Pasteur Institute 2020-2022). Maria Carolina Peixoto Rodrigues is supported by a postdoctoral fellowship E-26/202.024/2022(276047) – FAPERJ. | |
| Language | eng | en_US |
| Publisher | Elsevier | |
| Rights | open access | |
| Title | Shark-on-a-dish: elasmobranch cell cultures as a promising tool for the conservation of threatened species | en_US |
| Type | Article | |
| DOI | 10.1016/j.marpolbul.2024.117349 | |
| Abstract | Anthropogenic activities have increasingly contaminated aquatic ecosystems worldwide, requiring the development of adequate methods to assess the effects of environmental pollution on aquatic biota. Currently, ecotoxicological research on fish is largely based on in vivo studies, many times using post-mortem fish samples bought in fish markets or obtained through capture-and-release programs. However, such samples provide a narrow window to the cellular and molecular processes that occur to fish upon exposure to pollutants and other toxicants or pathogens. In thi sense, in vitro cell culture systems have been increasingly proven a valuable tool in several research fields, from molecular biology studies to conservation efforts. To date, however, cell cultures obtained from bony fish have been the most studied and with the best-described protocols and models. Elasmobranchs, comprising shark and rays, play important trophic and environmental roles, employed as chemical contamination environmental sentinels, suffering the effects of such contamination due to bioaccumulation and biomagnification processes. For these reasons, the development of new experimental tools to study elasmobranch cellular and molecular responses to environmental stimuli in controlled conditions is highly desirable. However, only some research groups have attempted to develop elasmobranch cell culture protocols to be used in an ecotoxicological context. In this sense, this review discusses the current elasmobranch cell culture scenario, its importance and potential applications in ecotoxicology assessments and conservation actions. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Estrutural. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Estrutural. Rio de Janeiro, RJ, Brasil / University of Miami. Miller School of Medicine. Bascom Palmer Eye Institute. Department of Ophthalmology. Laboratory of Ocular Immunology and Transplantation. Miami, FL, USA. | |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Biologia. Departamento de Biologia Marinha. Laboratório de Biologia e Tecnologia Pesqueira. Rio de Janeiro, RJ, Brasil / Instituto Museu Aquário Marinho do Rio de Janeiro. Aquário Marinho do Rio de Janeiro. Centro de Pesquisa. Rio de Janeiro, RJ, Brasil / Aquário Marinho do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil. | |
| Subject | Chondrichthyes | en_US |
| Subject | Cell culture | en_US |
| Subject | Ecotoxicology | en_US |
| Subject | Conservation | en_US |
| e-ISSN | 1879-3363 | |
| xmlui.metadata.dc.subject.ods | 09 Indústria, inovação e infraestrutura | |
| xmlui.metadata.dc.subject.ods | 14 Vida na água | |
| xmlui.metadata.dc.subject.ods | 15 Vida terrestre | |
| xmlui.metadata.dc.subject.ods | 17 Parcerias e meios de implementação | |
