| Author | Poester, Vanice Rodrigues | |
| Author | Xavier, Melissa Orzechowski | |
| Author | Munhoz, Lívia Silveira | |
| Author | Basso, Rossana Patricia | |
| Author | Zancopé-Oliveira, Rosely Maria | |
| Author | Freitas, Dayvison Francis Saraiva | |
| Author | Pasqualotto, Alessandro Comarú | |
| Access date | 2024-12-19T01:20:06Z | |
| Available date | 2024-12-19T01:20:06Z | |
| Document date | 2024 | |
| Citation | POESTER, Vanice Rodrigues et al. Sporothrix brasiliensis Causing Atypical Sporotrichosis in Brazil: A Systematic Review. Journal of Fungi, v. 10, n. 4, p. 1-16, Apr. 2024. | en_US |
| ISSN | 2309-608X | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/67700 | |
| Sponsorship | This research received no external funding. | en_US |
| Language | eng | en_US |
| Publisher | MDPI | en_US |
| Rights | open access | en_US |
| Title | Sporothrix brasiliensis Causing Atypical Sporotrichosis in Brazil: A Systematic Review | en_US |
| Type | Article | en_US |
| DOI | 10.3390/jof10040287 | |
| Abstract | Zoonotic sporotrichosis, a subcutaneous mycosis caused by Sporothrix brasiliensis, has become hyperendemic and a serious public health issue in Brazil and an emerging disease throughout the world. Typical sporotrichosis is defined as fixed or lymphocutaneous lesion development, however, reports of atypical presentations have been described in hyperendemic areas, which may result in a worse prognosis. Thus, considering an increase in atypical cases and in more severe extracutaneous cases and hospitalizations reported in Brazil, we aimed to perform a systematic review to search for hypersensitivity reactions (HRs) and extracutaneous presentations associated with zoonotic sporotrichosis. A systematic review was performed, following the PRISMA guidelines to search for atypical/extracutaneous cases (mucosal, osteoarthritis, HRs, pulmonary, meningeal) of zoonotic sporotrichosis. A total of 791 published cases over 26 years (1998-2023) in eleven Brazilian states were reviewed. Most cases corresponded to a HR (47%; n = 370), followed by mucosal (32%; n = 256), multifocal (8%; n = 60), osteoarthritis (7%; n = 59), meningeal (4%; n = 32), and pulmonary (2%; n = 14) infections. When available (n = 607), the outcome was death in 7% (n = 43) of cases. Here, we show a frequent and worrisome scenario of zoonotic sporotrichosis in Brazil, with a high and dispersed incidence of atypical/extracutaneous cases throughout the Brazilian territory. Therefore, educational measures are necessary to make health professionals and the overall population aware of this fungal pathogen in Brazil as well as in other countries in the Americas. | en_US |
| Affilliation | Universidade Federal do Rio Grande. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Saúde. Rio Grande, RS, Brasil / Universidade Federal do Rio Grande. Faculdade de Medicina. Mycology Laboratory. Rio Grande, RS, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio Grande. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Saúde. Rio Grande, RS, Brasil / Universidade Federal do Rio Grande. Faculdade de Medicina. Mycology Laboratory. Rio Grande, RS, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio Grande. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Saúde. Rio Grande, RS, Brasil / Universidade Federal do Rio Grande. Faculdade de Medicina. Mycology Laboratory. Rio Grande, RS, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio Grande. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Saúde. Rio Grande, RS, Brasil / Universidade Federal do Rio Grande. Faculdade de Medicina. Mycology Laboratory. Rio Grande, RS, Brasil / Universidade Federal do Rio Grande. Hospital Universitário Dr. Miguel Riet Correa Jr. Rio Grande, RS, Brasil / Empresa Brasileira de Serviços Hospitalares. Rio Grande, RS, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clíınica em Dermatologia Infecciosa. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Santa Casa de Misericórdia de Porto Alegre. Hospital Dom Vicente Scherer. Laboratório de Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal de Ciências da Saúde de Porto Alegre. Departamento de Medicina. Porto Alegre, RS, Brasil. | en_US |
| Subject | Zoonosis | en_US |
| Subject | Ocular | en_US |
| Subject | Nasal | en_US |
| Subject | Hypersensitivity | en_US |
| Subject | Osteoarthritis | en_US |
| Subject | Pulmonary | en_US |
| Subject | Meningeal disease | en_US |
| e-ISSN | 2309-608X | |
