| Author | Jamaluddine, Zeina | |
| Author | Idueta, Lorena Suarez | |
| Author | Paixao, Enny S. | |
| Author | Pescarini, Julia M. | |
| Author | Ghattas, Hala | |
| Author | Sato, Miho | |
| Author | Seita, Akihiro | |
| Author | Martinez-Juarez, Luis A. | |
| Author | Barreto, Mauricio L. | |
| Author | Ohuma, Eric O. | |
| Author | Day, Louise T. | |
| Author | Campbell, Oona M. R. | |
| Author | Blencowe, Hannah | |
| Access date | 2025-01-28T15:21:37Z | |
| Available date | 2025-01-28T15:21:37Z | |
| Document date | 2024 | |
| Citation | JAMALUDDINE, Zeina et al. Post-term births as a risk factor for small for gestational age births and infant mortality in Brazil, Mexico, and Palestinian refugees: an analysis of electronic birth records. Paediatric and Perinatal Epidemiology, p.1-10, 2024. | en_US |
| ISSN | 1365-3016 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/68290 | |
| Sponsorship | Nagasaki University. | en_US |
| Language | eng | en_US |
| Publisher | Wiley | en_US |
| Rights | restricted access | |
| Title | Post-term births as a risk factor for small for gestational age births and infant mortality in Brazil, Mexico, and Palestinian refugees: an analysis of electronic birth records | en_US |
| Type | Article | |
| DOI | 10. 1016/j.lana.2024. 100791 | |
| Abstract | Background: Post-term pregnancy, defined as reaching or exceeding 42 + 0 weeks of gestation, is known to be associated with unfavourable birth outcomes. High-income countries have responded to this risk by widely adopting labour induction protocols in late-term, but many low- and middle-income countries have not. However, understanding underlying mechanisms linking post-term births to adverse newborn and infant outcomes remains limited. Objective: To investigate the (a) prevalence of post-term, (b) the risk factors associated with post-term (c) the association between post-term births and the risk of small-for-gestational-age (SGA) neonates and of infant mortality in middle-income settings. Methods: We used existing electronic datasets from the general population of Brazil, Mexico, and Palestinian refugees. Regression models were used to explore the associations between post-term birth and SGA and infant mortality. Results: We analysed 21,335,033 live births in Brazil (2011-2018), 23,416,126 in Mexico (2008-2019), and 966,102 in Palestinian refugees (2010-2020) (N = 45,717,261). Post-term deliveries accounted for 3.1% of births in Brazil, 1.2% in Mexico, and 2.1% in Palestinian refugees. Post-term births had approximately three times the risk of resulting in SGA neonates compared to term births. Additionally, post-term neonates exhibited a 15% to 40% increased risk of infant mortality compared to term infants. Notably, post-term SGA neonates faced a significantly increased risk of infant mortality compared to term appropriate for gestational age neonates. Conclusions: These findings emphasise the critical significance of implementing induction strategies to prevent post-term pregnancies and mitigate the associated risks of SGA neonates and subsequent infant mortality. Moreover, the study highlights the importance of accurately determining gestational age and using INTERGROWTH-21st charts to improve the identification of SGA cases, enabling targeted interventions. This is especially relevant because post-term SGA neonates may not exhibit low birthweight (a commonly used risk marker) and, therefore, may miss out on required specialised attention. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK / School of Tropical Medicine and Global Health. Nagasaki University. Nagasaki, Japan. | en_US |
| Affilliation | Mexican Society of Public Health. Mexico City, Mexico. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para Saúde. Salvador, BA, Brasil. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para Saúde. Salvador, BA, Brasil. | en_US |
| Affilliation | Department of Health Promotion, Education, and Behavior. University of South Carolina. Columbia, South Carolina, USA. | en_US |
| Affilliation | School of Tropical Medicine and Global Health. Nagasaki University. Nagasaki, Japan. | en_US |
| Affilliation | United Nations Relief and Works Agency for Palestinian Refugees in the Near East. Amman, Jordan. | en_US |
| Affilliation | Mexican Society of Public Health. Mexico City, Mexico. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para Saúde. Salvador, BA, Brasil. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK. | en_US |
| Affilliation | Faculty of Epidemiology and Population Health. London School of Hygiene & Tropical Medicine. London, UK. | en_US |
| Subject | Electronic records | en_US |
| Subject | Foetal growth restriction | en_US |
| Subject | Indução | en_US |
| Subject | Infant mortality | en_US |
| Subject | Middle-income | en_US |
| Subject | Countries | en_US |
| Subject | Post-term | en_US |
| Subject | Gestation | en_US |
| Subject | Small for gestational age | en_US |
| DeCS | Registros eletrônicos de saúde | en_US |
| DeCS | Indução embrionária | en_US |
| DeCS | Mortalidade infantil | en_US |
| DeCS | Países em desenvolvimento | en_US |
| DeCS | Criança pós-termo | en_US |
| DeCS | Gravidez | en_US |
| DeCS | Recém-nascido pequeno para a idade gestacional | en_US |
| Embargo date | 2027 | |
