| Author | Carvalho, Anjo Gabriel | |
| Author | Rodrigues, Renata Santos | |
| Author | Rodrigues, Mariana Delfino | |
| Author | Oliveira, Letícia Pereira de | |
| Author | Belém, Mayra Gyovana Leite | |
| Author | Ricarte, Michelle Juliana Vieira Gomes | |
| Author | Dorneles, Nagilla Wynne dos Santos | |
| Author | Rocha, Paulo Ricardo Dell’Armelina | |
| Author | Lima, Núcia Cristiane da Silva | |
| Author | Lima, Claudete Martins | |
| Author | Watanabe, Michel | |
| Author | Pinto, Tatiana de Castro Abreu | |
| Author | Taborda, Roger Lafontaine Mesquita | |
| Author | Matos, Najla Benevides | |
| Access date | 2025-02-06T12:44:25Z | |
| Available date | 2025-02-06T12:44:25Z | |
| Document date | 2024 | |
| Citation | CARVALHO, Anjo Gabriel et al. Group B Streptococcus colonization prevalence and susceptibility profile in pregnant women in the Brazilian Amazon. Recife: Revista Brasileira de Saúde Materno Infantil, v. 24, n. e20230063, p. 1-10, 19 Jun. 2024. | en_US |
| ISSN | 1806-9804 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/68440 | |
| Language | eng | en_US |
| Publisher | SciELO | en_US |
| Rights | open access | en_US |
| Title | Group B Streptococcus colonization prevalence and susceptibility profile in pregnant women in the Brazilian Amazon | en_US |
| Type | Article | en_US |
| DOI | 10.1590/1806-9304202400000063-en | |
| Abstract | Objectives: to assess the prevalence and epidemiological factors associated with group B Streptococcus (GBS) colonization in pregnant women in Porto Velho City, Rondônia.
Methods: GBS was identified and isolated by genotypic and microbiological methods from rectovaginal samples of pregnant women between 35 and 37 weeks of gestation. Epidemiological data were collected using questionnaires and their correlation with colonization was assessed. The antimicrobial susceptibility profile was determined by disk diffusion method.
Results: a total of 22.5% (102/453) pregnant women were colonized with GBS. A higher level of colonization was observed at the vaginal tract (17.6%), compared to the rectal area. We did not find any sociodemographic or obstetric factors associated with an increased risk of GBS colonization. All strains were susceptible to antibiotics penicillin, ampicillin, cefazolin, and ceftriaxone. In contrast, the rates of resistance to tetracycline (74.1%), erythromycin (14.1%), and clindamycin (3.5%) were observed.
Conclusion: the prevalence of GBS as well as the absence of predictors of colonization demonstrated the need for universal screening for GBS in all pregnant women in the region. In addition, we showed that the first-line antibiotics recommended for prophylaxis are still good options for the prevention of neonatal GBS disease in the region. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Porto Velho, RO, Brasil / Fundação Universidade Federal de Rondônia. Programa de pós-graduação em Biologia Experimental. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Programa de Pós-Graduação em Biologia Celular e Molecular. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Faculdades Integradas Aparício Carvalho. Departamento de Enfermagem. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Faculdades Integradas Aparício Carvalho. Departamento de Enfermagem. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Laboratório de Microbiologia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Faculdades Integradas Aparício Carvalho. Departamento de Enfermagem. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Laboratório de Microbiologia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Laboratório de Microbiologia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Centro de Pesquisa em Medicina Tropical de Rondônia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Governo de Rondônia. Secretaria de Saúde do Estado de Rondônia. Hospital de Base Dr. Ary Pinheiro. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Universidade Federal de Rondônia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Laboratório de Microbiologia. Porto Velho, RO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Laboratório de Microbiologia. Porto Velho, RO, Brasil. | en_US |
| Subject | Antibiotic resistance | en_US |
| Subject | Neonatal diseases | en_US |
| Subject | Antibiotic prophylaxis | en_US |
| Subject | Public health surveillance | en_US |
| Subject | Pregnant women | en_US |
| DeCS | Drug Resistance, Microbial | en_US |
| DeCS | Infant, Newborn, Diseases | en_US |
| DeCS | Antibiotic Prophylaxis | en_US |
| DeCS | Public Health Surveillance | en_US |
| DeCS | Pregnant Women | en_US |
