| Author | Branda, Francesco | |
| Author | Ceccarelli, Giancarlo | |
| Author | Giovanetti, Marta | |
| Author | Albanese, Mattia | |
| Author | Binetti, Erica | |
| Author | Ciccozzi, Massimo | |
| Author | Scarpa, Fabio | |
| Access date | 2025-02-14T14:30:18Z | |
| Available date | 2025-02-14T14:30:18Z | |
| Document date | 2025 | |
| Citation | BRANDA, Francesco et al. Nipah Virus: A Zoonotic Threat Re-Emerging in the Wake of Global Public Health Challenges. Microorganisms, v. 13, p. 1-24, Jan. 2025. | en_US |
| ISSN | 2076-2607 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/68573 | |
| Language | eng | en_US |
| Publisher | MDPI | en_US |
| Rights | open access | en_US |
| Title | Vírus Nipah: Uma ameaça zoonótica que ressurge na esteira dos desafios globais de saúde pública | en_US |
| Type | Article | en_US |
| DOI | 10.3390/microorganisms13010124 | |
| Abstract | The re-emergence of the Nipah virus (NiV) in Kerala, India, following the tragic death of a 14-year-old boy, underscores the persistent threat posed by zoonotic pathogens and highlights the growing global public health challenge. With no vaccine or curative treatment available, and fatality rates as high as 94% in past outbreaks, the Nipah virus is a critical concern for health authorities worldwide. Transmitted primarily through contact with fruit bats or consumption of contaminated food, as well as direct human-to-human transmission, NiV remains a highly lethal and unpredictable pathogen. The World Health Organization has classified Nipah as a priority pathogen due to its alarming potential to cause widespread outbreaks and even trigger the next pandemic. Recent outbreaks in India and Bangladesh, occurring with seasonal regularity, have once again exposed the vulnerability of public health systems in containing this virus. This study explores the epidemiology, ecological factors driving transmission, and the public health response to NiV, emphasizing the role of zoonotic spillovers in pandemic preparedness. As the global community grapples with an increasing number of emerging infectious diseases, the Nipah virus stands as a stark reminder of the importance of coordinated surveillance, rapid containment measures, and the urgent development of novel strategies to mitigate the impact of this re-emerging threat. | en_US |
| Affilliation | Unit of Medical Statistics and Molecular Epidemiology. Università Campus Bio-Medico di Roma. Rome, Italy. | en_US |
| Affilliation | Department of Public Health and Infectious Diseases. University of Rome Sapienza. Rome, Italy / Internal Medicine. Endocrine-Metabolic Sciences and Infectious Diseases. Azienda Ospedaliero Universitaria Umberto I. Rome, Italy / Migrant and Global Health Research Organization. Mi-Hero, Italy. | en_US |
| Affilliation | Department of Science and Technologies for Sustainable Development and One Health. Università Campus Bio-Medico di Roma. Rome, Italy / Fundacão Oswaldo Cruz Instituto René Rachou. Belo Horizonte, MG, Brasil / Doenças Amplificadas pelo Clima e Epidemias nas Américas. Belo Horizonte, MG, Brasil. | en_US |
| Affilliation | Department of Public Health and Infectious Diseases. University of Rome Sapienza. Rome, Italy / Hospital of Tropical Diseases. Mahidol University. Bangkok, Thailand. | en_US |
| Affilliation | Department of Public Health and Infectious Diseases. University of Rome Sapienza. Rome, Italy / Hospital of Tropical Diseases. Mahidol University. Bangkok, Thailand. | en_US |
| Affilliation | Unit of Medical Statistics and Molecular Epidemiology. Università Campus Bio-Medico di Roma. Rome, Italy. | en_US |
| Affilliation | Department of Biomedical Sciences. University of Sassari, Italy. | en_US |
| Subject | Nipah virus | en_US |
| Subject | Zoonotic pathogens | en_US |
| Subject | Global health | en_US |
| Subject | Surveillance | en_US |
