Author | Clapis, Franciele C. Meireles | |
Author | Martins, Maria Auxiliadora | |
Author | Japur, Camila Cremonezi | |
Author | Martins Filho, Olindo Assis | |
Author | Évora, Paulo Roberto Barbosa | |
Author | Basile Filho, Aníbal | |
Access date | 2013-09-09T16:29:38Z | |
Available date | 2013-09-09T16:29:38Z | |
Document date | 2010 | |
Citation | CLAPIS, Franciele C. et al. Meireles et al. Mechanical ventilation mode (volume × pressure) does not change the variables obtained by indirect calorimetry in critically ill patients. J. Crit. Care., v. 25, n. 4, p. 659.e9–659.e16, Dec. 2010. | pt_BR |
ISSN | 0883-9441 | |
URI | https://www.arca.fiocruz.br/handle/icict/6860 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | |
Title | Mechanical ventilation mode (volume × pressure) does not change the variables obtained by indirect calorimetry in critically ill patients | pt_BR |
Type | Article | |
DOI | 10.1016/j.jcrc.2009.11.010. | |
Abstract | Purpose:The aim of the study was to analyze the difference between the results obtained by indirect calorimetry (IC) using volume-controlled and pressure-controlled mechanical ventilation in 2 different ventilators and to characterize the variables achieved by IC after well-defined changes in minute volume (Vm).
Materials and Methods: Prospective study of 20 critically ill patients under volume-controlled (n = 15) or pressure-controlled (n = 5) mechanical ventilation. Three IC measurements of 45 minutes each were taken; values of oxygen consumption (VO2), carbon dioxide production (VCO2), Vm, resting energy expenditure (REE), and respiratory quotient (RQ) were obtained. For the last measurement, Vm was set at 20% above the baseline.
Results: There were no differences between the results obtained by IC during volume-controlled and pressure-controlled mechanical ventilation. The most relevant changes in the variables obtained by IC before and after intervention in Vm were a significant increase in VCO2(from 165 to 177 mL•min−1; P b.01), a decrease in PaCO2 (from 38.49 to 28.46 mm Hg;Pb.01), and a rise in pH (from 7.41 to 7.49;Pb.01). There were no alterations in VO2, REE, or RQ.
Conclusions: Ventilators and ventilation modes do not influence the IC measurements. The observed changes have no clinical effects and are reversible, provided that increased Vm is maintained for no longer than 45 minutes | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Divisão de Terapia Intensiva. Ribeirão Preto, SP, Brazil. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Divisão de Terapia Intensiva. Ribeirão Preto, SP, Brazil. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Divisão de Terapia Intensiva. Ribeirão Preto, SP, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Biomarcadores de Diagnóstico e Monitoração. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. | pt_BR |
Affilliation | Divisão de Terapia Intensiva, Departamento de Cirurgia e Anatomia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. | pt_BR |
Subject | Indirect calorimetry | pt_BR |
Subject | Mechanical ventilation | pt_BR |
Subject | ICU setting | pt_BR |
Subject | VO2 | pt_BR |
Subject | VCO2 | pt_BR |