| Author | Santos, Thays Figueiroa dos | |
| Author | Bueno, Marina Galvão | |
| Author | Moura, Patricia Emilia Bento | |
| Author | Oliveira, Marcione Brito de | |
| Author | Cordeiro, José Luís Passos | |
| Author | Cavalcante, Nádia Maria da Cruz Santos | |
| Author | Mazzarotto, Giovanny Augusto Camacho Antevere | |
| Author | Wallau, Gabriel da Luz | |
| Author | Silva Junior, Leonardo Corrêa da | |
| Author | Resende, Paola Cristina | |
| Author | Siqueira, Marilda Agudo Mendonça Teixeira de | |
| Author | Ogrzewalska, Maria | |
| Access date | 2025-02-21T13:39:47Z | |
| Available date | 2025-02-21T13:39:47Z | |
| Document date | 2025 | |
| Citation | SANTOS, Thays Figueiroa dos et al. Alpha and betacoronavirus detection in neotropical bats from Northeast Brazil suggests wide geographical distribution and persistence in natural populations. Animals, v. 15, n. 3, p. 1-18, 24 Jan. 2025. | |
| ISSN | 2076-2615 | |
| URI | https://www.arca.fiocruz.br/handle/icict/68670 | |
| Description | Produção científica do Laboratório de Virologia Comparada e Ambiental. | pt_BR |
| Description | Produção científica do Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. | pt_BR |
| Description | Simple Summary: Our world is facing an urgent challenge with the rise of zoonotic viral diseases like COVID-19, emphasizing the critical need to understand viruses in wildlife. Bats, comprising about 20% of mammalian species globally, are known reservoirs for many pathogens, including coronaviruses. This study focused on investigating the presence and variety of coronaviruses in bat populations from northeastern Brazil, particularly in Ceará, where bat pathogen research is scarce. Over a year, we collected oral and rectal swabs from 298 bats across three municipalities. Our molecular analyses unveiled alphacoronaviruses in several bat species, and we identified a new type of Betacoronavirus in Artibeus planirostris, broadening our understanding of the coronavirus diversity in Brazilian bats. Furthermore, our findings suggest that closely related coronavirus strains can infect various bat species in distant Brazilian regions and habitats. While we did not find SARS-CoV-2 or influenza A viruses in the sampled bats, our study emphasizes the need for ongoing surveillance to detect and track zoonotic viruses circulating in wildlife populations, which is crucial for preventing future pandemics. | en_US |
| Sponsorship | This study was founded by Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico (FUNCAP, no 06347980/2020), with scholarship to Patricia Emilia Bento Moura, and partly funded by Reference laboratories from Oswaldo Cruz Foundation (CVSLR/FIOCRUZ), Oswaldo Cruz Institute. | |
| Language | eng | en_US |
| Publisher | MDPI | |
| Rights | open access | |
| Title | Alpha and betacoronavirus detection in neotropical bats from Northeast Brazil suggests wide geographical distribution and persistence in natural populations | en_US |
| Type | Article | |
| DOI | 10.3390/ani15030332 | |
| Abstract | The emergence of zoonotic viral diseases, notably exemplified by the recent coronavirus disease pandemic in 2019 (COVID-19), underscores the critical need to understand the dynamics of viruses circulating in wildlife populations. This study aimed to investigate the diversity of coronaviruses in bat populations from northeastern Brazil, particularly in the state of Ceará, where little research on bat pathogens has been conducted previously. Bat sampling was performed between March 2021 and March 2022 across three municipalities, resulting in the collection of oral and rectal swabs from 298 captured individuals. Molecular analyses revealed alphacoronaviruses in multiple bat species. Additionally, a novel Betacoronavirus was identified in Artibeus planirostris, which did not fall within an established subgenus. Phylogenetic placement of these new coronavirus sequences suggests that closely related coronavirus lineages can infect a wide range of bat species sampled in distantly related Brazilian states and biomes. No SARS-CoV-2 and influenza A viruses were found in the sampled bats. These findings expand our understanding of coronavirus diversity in Brazilian bats. The detection of coronaviruses in various bat species underscores the importance of bats as reservoirs for these viruses. The absence of SARS-CoV-2 in the sampled bats indicates a lack of spillback events from human or environmental sources. However, the potential for future transmission events underscores the importance of ongoing surveillance and transmission mitigation protocols in wildlife management practices. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidade Federal do Rio de Janeiro. Fórum de Ciência e Cultura. Museu Nacional. Conselho Departamental. Departamento de Vertebrados. Setor de Mastozoologia. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Ceará. Área de Saúde e Ambiente. Eusébio, CE, Brasil / Fundação Oswaldo Cruz. Plataforma Internacional para Ciência, Tecnologia e Inovação em Saúde. Ílhavo, Portugal. | |
| Affilliation | Universidade Estadual do Ceará. Museu de História Natural do Ceará Prof. Dias da Rocha. Pacoti, CE, Brasil / Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Ceará. Laboratório Analítico de Competências Moleculares e Epidemiológicas. Plataforma de Camelídeos e Produção de Nanocorpos. Eusébio, CE, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Bioinformática. Recife, PE, Brasil / National Reference Center for Tropical Infectious Diseases. WHO Collaborating Center for Arbovirus and Hemorrhagic Fever Reference and Research. Bernhard Nocht Institute for Tropical Medicine. Department of Arbovirology and Entomology. Hamburg, Germany. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios, Exantemáticos, Enterovírus e Emergências Virais. Rio de Janeiro, RJ, Brasil. | |
| Subject | Chiroptera | en_US |
| Subject | Zoonosis | en_US |
| Subject | Respiratory viruses | en_US |
| Subject | South America | en_US |
| Subject | Coronaviruses | en_US |
| DeCS | RNA Polimerase Dependente de RNA | pt_BR |
| e-ISSN | 2076-2615 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 15 Vida terrestre | |
