| Author | Lopes, Rafael | |
| Author | Basagaña, Xavier | |
| Author | Bastos, Leonardo S. L. | |
| Author | Bozza, Fernando A. | |
| Author | Ranzani, Otavio T. | |
| Access date | 2025-03-10T20:42:34Z | |
| Available date | 2025-03-10T20:42:34Z | |
| Document date | 2024 | |
| Citation | LOPES, Rafael et al. Ambient temperature and dengue hospitalization in Brazil: A 10-year period case time series analysis. Environmental Epidemiology, v. 9, n. 1, p. 1-8, Dec. 2024. | en_US |
| ISSN | 2474-7882 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/68880 | |
| Sponsorship | Supported by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil (Finance Code 001 to R.L.), Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil (grant number: 141698/2018-7 to R.L.; grant number 420096/2023-0 to L.S.L.B.), and Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, Brazil (E-26/204.520/2024 to L.S.L.B.). O.T.R. is funded by a Sara Borrell fellowship (CD19/00110) from the Instituto de Salud Carlos III. O.T.R. acknowleges support from the grant CEX2023-0001290-S funded by MCIN/AEI/10.13039/501100011033 and from the Generalitat de Catalunya through the CERCA Program. The funding agencies had no role in the conceptualization of the study. | en_US |
| Language | eng | en_US |
| Publisher | Wolters Kluwer | en_US |
| Rights | open access | en_US |
| Title | Ambient temperature and dengue hospitalization in Brazil: A 10-year period case time series analysis | en_US |
| Type | Article | en_US |
| DOI | 10.1097/EE9.0000000000000360 | |
| Abstract | Background: Dengue has an increased worldwide epidemic potential with the global rising temperature due to climate change. Heat and rainfall are known to influence seasonal patterns of dengue transmission over the course of weeks to months. However, there is a gap in knowledge about the short-term effect of heat on dengue severity. We aimed to quantify the effect of ambient temperature on dengue hospitalization risk in Brazil. Methods: Daily dengue hospitalization counts and average daily ambient temperature from 2010 to 2019 were analyzed from Brazil. We applied the case time series design combined with a distributed lag nonlinear model framework to estimate relative risk (RR) estimates for dose-response and lag-response structures for the association of temperature and dengue hospitalization. We estimate the overall dengue hospitalization RR for the whole country as well as for each of the five macroregions. Results: A total of 579,703 hospital admissions due to dengue occurred between 2010 and 2019. We observed a positive association between high temperatures and a high risk of hospitalization across the country. Under extreme heat (95th percentile of temperature), the RR was 3.47 (95% confidence interval: 2.88, 4.19) compared with minimum hospitalization risk. This association was mainly driven by an immediate effect of heat (lag 0) and was similar for the Northeast, Center-West, Southeast, and South regions, but unclear for the North. The risk was of greater magnitude among females and those aged ≥65 years. Conclusion: Short-term high temperatures are associated with an increase in the risk of hospitalization by dengue. | en_US |
| Affilliation | Universidade Estadual Paulista "Júlio de Mesquita Filho". Instituto de Física Teórica. São Paulo, SP, Brasil / Barcelona Institute for Global Health. ISGlobal. Universitat Pompeu Fabra. CIBER Epidemiología y Salud Pública. Barcelona, Spain. | en_US |
| Affilliation | Barcelona Institute for Global Health. ISGlobal. Universitat Pompeu Fabra. CIBER Epidemiología y Salud Pública. Barcelona, Spain. | en_US |
| Affilliation | Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Medicina Intensiva. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Barcelona Institute for Global Health. ISGlobal. Universitat Pompeu Fabra. CIBER Epidemiología y Salud Pública. Barcelona, Spain / Universidade de São Paulo. Faculdade de Medicina. Instituto do Coração. Divisão Pulmonar. São Paulo, SP, Brasil. | en_US |
| Subject | Dengue | en_US |
| Subject | Heat | en_US |
| Subject | Hospitalization | en_US |
| Subject | Temperature | en_US |
| e-ISSN | 2474-7882 | |
