| Author | Pereira, Cláudio Antônio de Moura | |
| Author | Mendes, Renata Pessôa Germano | |
| Author | Silva, Poliana Gomes da | |
| Author | Chaves, Elton José Ferreira | |
| Author | Pena, Lindomar José | |
| Access date | 2025-04-14T13:18:57Z | |
| Available date | 2025-04-14T13:18:57Z | |
| Document date | 2025 | |
| Citation | Pereira CAM, Mendes RPG, Silva PGD, Chaves EJF, Pena LJ. Vaccines Against Urban Epidemic Arboviruses: The State of the Art. Viruses. 2025 Mar 6;17(3):382. doi: 10.3390/v17030382. PMID: 40143310; PMCID: PMC11945797. | en_US |
| ISSN | 1999-4915 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/69617 | |
| Language | eng | en_US |
| Rights | open access | en_US |
| Title | Vaccines Against Urban Epidemic Arboviruses: The State of the Art | en_US |
| Type | Article | en_US |
| DOI | 10.3390/v17030382 | |
| Abstract | Arboviruses represent a contemporary global challenge, prompting coordinated efforts from health organizations and governments worldwide. Dengue, chikungunya, and Zika viruses have become endemic in the tropics, resulting in the so-called "triple arbovirus epidemic". These viruses are transmitted typically through the bites of infected mosquitoes, especially A. aegypti and A. albopictus. These mosquito species are distributed across all continents and exhibit a high adaptive capacity in diverse environments. When combined with unplanned urbanization, uncontrolled population growth, and international travel-the so-called "triad of the modern world"-the maintenance and spread of these pathogens to new areas are favored. This review provides updated information on vaccine candidates targeting dengue, chikungunya, and Zika viruses. Additionally, we discuss the challenges, perspectives, and issues associated with their successful production, testing, and deployment within the context of public health. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Laboratório de Virologia e Terapia Experimental (Lavite). Recife, PE, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Laboratório de Virologia e Terapia Experimental (Lavite). Recife, PE, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Laboratório de Virologia e Terapia Experimental (Lavite). Recife, PE, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Laboratório de Virologia e Terapia Experimental (Lavite). Recife, PE, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Laboratório de Virologia e Terapia Experimental (Lavite). Recife, PE, Brasil. | en_US |
| Subject | Emerging arboviruses | en_US |
| Subject | Mosquito-borne infections | en_US |
| Subject | Public health | en_US |
| Subject | Vaccine development | en_US |
