| Author | Domingues, Rosa Maria Soares Madeira | |
| Author | Dias, Marcos Augusto Bastos | |
| Author | Pereira, Ana Paula Esteves | |
| Author | Luz, Paula Mendes | |
| Author | Jalil, Emilia M. | |
| Author | Rabello, Angela Cristina Vasconcelos de Andrade | |
| Author | Friedman, Ruth Khalili | |
| Author | Leal, Maria do Carmo | |
| Access date | 2025-05-14T00:39:36Z | |
| Available date | 2025-05-14T00:39:36Z | |
| Document date | 2025 | |
| Citation | DOMINGUES, Rosa Maria Soares Madeira et al. Gestational and congenital syphilis in the state of Rio de Janeiro, Brazil, 2021‒2023. The Brazilian Journal of Infectious Diseases, v. 29, n. 3, p. 1-7, May/Jun. 2025. | en_US |
| ISSN | 1413-8670 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/70391 | |
| Sponsorship | This work was supported by the Secretaria de Ciência, Tecnologia e Inovação e do Complexo Econômico-Industrial da Saúde – SECTICS/MS [grant n◦ 25000.174797/2023-14], Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) [grant n◦ 443766/2018-5], Fundação Oswaldo Cruz Programa Inova Geração de Conhecimento [grant number VPPCB-007-FIO-18), The Newton Fund Institutional Links On Impact And Evidence-Based Policies (Health And Neglected Diseases) framework [grant n◦ 25380.002237/2020-81] and Fundação ao de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) /7ª Edição ao do programa Pesquisa para o SUS: gestão compartilhada em saúde – PPSUS [grant n◦ E-26/210.463/2021]. | en_US |
| Language | eng | en_US |
| Publisher | Elsevier | en_US |
| Rights | open access | en_US |
| Title | Gestational and congenital syphilis in the state of Rio de Janeiro, Brazil, 2021‒2023 | en_US |
| Type | Article | en_US |
| DOI | 10.1016/j.bjid.2025.104522 | |
| Abstract | Gestational (GS) and congenital syphilis (CS) are important public health problems in Brazil. This study aims to estimate the prevalence of GS, the incidence of CS and the rate of vertical transmission (VT) of syphilis, as well as to evaluate the management indicators of GS in the State of Rio de Janeiro (RJS), the Brazilian state with the highest detection rate of GS and incidence of CS in 2022. A hospital-based, cross-sectional study was carried out in public and private hospitals located in RJS, in the period 2021-2023, with interviews with 1,923 women, analysis of prenatal care (PNC) cards and hospital records. The GS management indicators, the prevalence of GS, the incidence of CS and the rate of VT were estimated with the respective 95 % confidence intervals (95 % CI), according to the source of financing for hospitalizations for childbirth or abortion care. PNC was reported by 93.7 % of women, 82.7 % had the first test for syphilis and 52.6 % the second. The prevalence of GS was estimated at 14.5 % (95 % CI 9.2 %- 22.2 %), with higher values in women with public financing (18.2 % public; 3.6 % private). Nearly one-third-of women with GS were diagnosed only during hospitalization for childbirth or abortion care and 13.4 % were appropriately treated during PNC. The incidence of CS was estimated at 53.1 per 1,000 live births (68.4 per 1,000 public; 9.7 per 1,000 LB private) with a VT rate of 33.5 %, with no difference according to the source of financing. The detection rate of GS and the incidence rate of CS were double those reported to the Brazilian Notifiable Diseases Information System. Several missed opportunities for the control of CS were identified. Women with public financing had a higher prevalence of GS and incidence of CS, and should be the priority target of control strategies. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | en_US |
| Subject | Syphilis | en_US |
| Subject | Pregnancy | en_US |
| Subject | Congenital syphilis | en_US |
| Subject | Prenatal care | en_US |
| Subject | Vertical transmission of infectious disease | en_US |
| Subject | Observational study | en_US |
| Subject | Brazil | en_US |
| e-ISSN | 1678-4391 | |
