Author | Webster, Joanne P. | |
Author | Oliveira, Guilherme Corrêa de | |
Author | Rollinson, David | |
Author | Gower, Charlotte M. | |
Access date | 2013-10-04T11:58:13Z | |
Available date | 2013-10-04T11:58:13Z | |
Document date | 2010 | |
Citation | WEBSTER, Joanne P. et al. Schistosome genomes: a wealth of information. Trends Parasitol. 2010 Mar;26(3):103-6. | pt_BR |
ISSN | 1471-4922 | |
URI | https://www.arca.fiocruz.br/handle/icict/7086 | |
Language | eng | pt_BR |
Publisher | Elsevier Science | pt_BR |
Rights | restricted access | pt_BR |
Title | Schistosome genomes: a wealth of information. | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.pt.2009.12.006 | |
Abstract | The blood flukes Schistosoma japonicum and Schistosoma mansoni are the first major human platyhelminth pathogens to have their genome sequences published. The work of two large international consortia offers draft sequence information and detailed analyses presenting a wealth of information addressing, in particular, metabolic and signalling pathways, host-parasite interactions and potential new drug targets. We comment on these breakthroughs and their potential applications in the study and control of schistosomes. | pt_BR |
Affilliation | Imperial College. Faculty of Medicine. Department of Infectious Disease Epidemiology. London, UK | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. CEBio. Instituto Nacional de Ciencia e Tecnologia em Doenças Tropicais. Belo Horizonte, MG, Brazil | pt_BR |
Affilliation | Natural History Museum. Department of Zoology. Wolfson Wellcome Biomedical Laboratories. London, UK | pt_BR |
Affilliation | Imperial College. Faculty of Medicine. Department of Infectious Disease Epidemiology. London, UK | pt_BR |
Subject | Drug Design | pt_BR |
Subject | Genome, Helminth/genetics | pt_BR |
Subject | Humans | pt_BR |
Subject | Schistosoma/genetics | pt_BR |
Subject | Schistosomiasis/drug therapy | pt_BR |