| Author | Barreto, Tatiane Oliveira | |
| Author | Cleto, Lorena Sabino | |
| Author | Gioda, Carolina Rosa | |
| Author | Silva, Renata Sabino | |
| Author | Azevedo, Ana Carolina Campi | |
| Author | Franco, Junia de Sousa | |
| Author | Magalhães, José Carlos de | |
| Author | Penaforte, Claudia Lopes | |
| Author | Pinto, Kelerson Mauro de Castro | |
| Author | Cruz, Jader dos Santos | |
| Author | Vieira, Etel Rocha | |
| Access date | 2014-02-28T14:05:24Z | |
| Available date | 2014-02-28T14:05:24Z | |
| Document date | 2012 | |
| Citation | BARRETO, Oliveira Barreto et al. . Swim training does not protect mice from skeletal muscle oxidative damage following a maximum exercise test. European Journal of Applied Physiology. 2012, vol.112, pp. 2523-2530. | pt_BR |
| ISSN | 1439-6319 | |
| URI | https://www.arca.fiocruz.br/handle/icict/7374 | |
| Language | eng | pt_BR |
| Publisher | Springer-Verlag | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Swim training does not protect mice from skeletal muscle oxidative damage following a maximum exercise test | pt_BR |
| Type | Article | |
| Abstract | We investigated whether swim training protects skeletal muscle from oxidative damage in response to a maximum progressive exercise. First, we investigated the effect of swim training on the activities of the antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), in the gastrocnemiusmuscle of C57Bl/6mice, 48 h after the last training session.Mice swam for 90 min, twice a day, for 5 weeks at 31_C (±1_C). The activities of SOD and CAT were increased in trained mice (P\0.05) compared to untrained group. However, no effect of training was observed in the activity of GPx. In a second experiment, trained and untrained mice were submitted to a
maximum progressive swim test. Compared to control mice (untrained, not acutely exercised), malondialdehyde (MDA) levels were increased in the skeletal muscle of both trained and untrained mice after maximum swim. The activity of GPx was increased in the skeletal muscle of both trained and
untrained mice, while SOD activity was increased only in trained mice after maximum swimming. CAT activity was increased only in the untrained compared to the control group. Although the trained mice showed increased activity of citrate synthase in skeletal muscle, swim performance was not different compared to untrained mice. Our results show an imbalance in the activities of SOD, CAT and GPx in
response to swim training, which could account for the oxidative damage observed in the skeletal muscle of trained mice in response to maximum swim, resulting in the absence of improved exercise performance. | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Department of Biochemistry and Immunology. Laboratory of Excitable Membranes. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Federal University of Rio Grande. Biological Science Institute. Rio Grande, RS, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil/ Oswaldo Cruz Foundation. Rene Rachou Research Center. Laboratory of Diagnosis Biomarkers and Monitoration. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil/ Federal University of São João del Rey. São João del Rey, MG, Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil/ Federal University of São João del Rey. São João del Rey, MG, Brazil | pt_BR |
| Affilliation | Federal University of Ouro Preto. CEDUFOP. Ouro Preto, MG,Brazil | pt_BR |
| Affilliation | University Center of Belo Horizonte. Department of Biological. Environmental and Health Sciences. Belo Horizonte, MG, Brazil/ Universidade Federal de Minas Gerais. Department of Biochemistry and Immunology. Laboratory of Excitable Membranes. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Federal University of Jequitinhonha and Mucuri Valleys. Laboratory of Immunology. Diamantina, MG, Brazil | pt_BR |
| Subject | Swim | pt_BR |
| Subject | Oxidative stress | pt_BR |
| Subject | Superoxide dismutase | pt_BR |
| Subject | Catalase | pt_BR |
| Subject | Glutathione peroxidase | pt_BR |
| Subject | Exercise performance | pt_BR |
