| Author | Reis, Mitermayer Galvão dos | |
| Author | Kuhns, Janet | |
| Author | Blanton, Ronald Edward | |
| Author | Davis, Alan H. | |
| Access date | 2014-05-06T12:13:21Z | |
| Available date | 2014-05-06T12:13:21Z | |
| Document date | 1989 | |
| Citation | REIS, M. G. dos et al. Localization and pattern of expression of a female specific mRNA in Schistosoma mansoni. Molecular Biochemical and Parasitology, v. 32, n. 2-3, p. 113-119, 1989. | pt_BR |
| ISSN | 0166-6851 | |
| URI | https://www.arca.fiocruz.br/handle/icict/7582 | |
| Language | eng | pt_BR |
| Publisher | Elsevier Science Publishers B.V. | pt_BR |
| Rights | open access | pt_BR |
| Title | Localization and pattern of expression of a female specific mRNA in Schistosoma mansoni | pt_BR |
| Type | Article | pt_BR |
| Abstract | To understand mechanisms involved m sex-specific gene expression in Schistosoma mansoni, a cDNA (fs800) was isolated that
hybridized to an 800 nucleotide mRNA present in high levels only in mature female worms. The fs800 cDNA sequence was characterized
by two long open reading frames and central stretches of repeated amino acids. Fs800 did not share similarities with
other known sequences in computer searches. In situ hybridization, however, revealed that the mRNA corresponding to fs800 was
found only in female vitelline cells, suggesting that the product of this gene may be involved in the production or function of eggs.
Fs800 is developmentally regulated as expression of this gene is dependent on the maturity of female worms. Furthermore, during
in vitro culture, when female worms are known to stop egg production, expression of fs800 selectively ceased. | pt_BR |
| Affilliation | Escola de Medicina e Saude Publica. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Division of Geographic Medicine. Department of Medicine. Maryland, USA | pt_BR |
| Affilliation | Division of Geographic Medicine. Department of Medicine. Maryland, USA | pt_BR |
| Affilliation | Division of Geographic Medicine. Department of Medicine. Maryland, USA / Department of Molecular Biology and Microbiology. Case Western Reserve University and University Hospitals. Cleveland, OH, USA | pt_BR |
| Subject | Female specific cDNA | pt_BR |
| Subject | In situ hybridization | pt_BR |
| Subject | Gene localization | pt_BR |
| Subject | Gene expression; | pt_BR |
| Subject | Vitelline cell | pt_BR |
| DeCS | RNA Mensageiro/genética | pt_BR |
| DeCS | Schistosoma mansoni/genética | pt_BR |
| DeCS | Ducto Vitelino | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Sequência de Bases | pt_BR |
| DeCS | Sondas de DNA | pt_BR |
| DeCS | Feminino | pt_BR |
| DeCS | Regulação da Expressão Gênica | pt_BR |
| DeCS | Oviposição | pt_BR |
| DeCS | Sondas RNA | pt_BR |
| DeCS | Caracteres Sexuais | pt_BR |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
