Author | Cunha, Andréa Mendonça Gusmão | |
Author | Araujo, Adele Caterino de | |
Author | Costa, Sandra Cecilia Botelho | |
Author | Fortuna, Elisabeth Santos | |
Author | Boa-Sorte, Ney Cristian Amaral | |
Author | Gonçalves, Marilda de Souza | |
Author | Costa, Fernando Ferreira | |
Author | Castro Filho, Bernardo Galvão | |
Access date | 2014-08-04T19:12:55Z | |
Available date | 2014-08-04T19:12:55Z | |
Document date | 2005 | |
Citation | CUNHA, A. M. G. et al. Increasing seroprevalence of human herpesvirus 8 (HHV-8) with age confirms HHV-8 endemicity in Amazon Amerindians from Brazil. Journal of General Virology, v. 86, pt 9, p. 2433-2437, 2005. | pt_BR |
ISSN | 0022-1317 | |
URI | https://www.arca.fiocruz.br/handle/icict/8128 | |
Language | eng | pt_BR |
Publisher | Society for General Microbiology | pt_BR |
Rights | open access | pt_BR |
Title | Increasing seroprevalence of human herpesvirus 8 (HHV-8) with age confirms HHV-8 endemicity in Amazon Amerindians from Brazil. | pt_BR |
Type | Article | pt_BR |
DOI | 10.1099/vir.0.81087-0 | |
Abstract | Human herpesvirus 8 (HHV-8) seroprevalences were determined in two isolated Amazon
Amerindian tribes, according to age, gender and familial aggregation. Plasma and serum samples
obtained from 982 Amazon Amerindians (664 Tiriyo´ and 318 Waiampi) were tested for
antibodies against lytic and latent HHV-8 antigens by using ‘in-house’ immunofluorescence
assays. Overall, HHV-8 seroprevalence was 56?8% (57?4% in the Tiriyo´ tribe and 55?7% in
the Waiampi tribe). Seroprevalence was independent of gender and increased linearly with age:
it was 35?0% among children aged 2–9 years, 51?4% in adolescents (10–19 years), 72?9%
in adults and 82?3% in adults aged >50 years. Interestingly, 44?4% of children under 2 years
of age were HHV-8-seropositive. No significant differences in seroprevalence between tribes and
age groups were detected. It is concluded that HHV-8 is hyperendemic in Brazilian Amazon
Amerindians, with vertical and horizontal transmission during childhood, familial transmission and
sexual contact in adulthood contributing to this high prevalence in these isolated populations. | pt_BR |
Affilliation | School of Medical Sciences. Departments of Clinical Pathology and Internal Medicine. State University of Campinas. Campinas, SP, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Adolfo Lutz Institute. Immunology Section. São Paulo, SP, Brasil | pt_BR |
Affilliation | School of Medical Sciences. Departments of Clinical Pathology and Internal Medicine. State University of Campinas. Campinas, SP, Brasil | pt_BR |
Affilliation | Adolfo Lutz Institute. Immunology Section. São Paulo, SP, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Bahiana Medical School. Bahiana Foundation for the Development of Sciences. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasi | pt_BR |
Affilliation | School of Medical Sciences. Departments of Clinical Pathology and Internal Medicine. State University of Campinas. Campinas, SP, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Bahiana Medical School. Bahiana Foundation for the Development of Sciences. Salvador, BA, Brasil | pt_BR |
DeCS | Anticorpos Antivirais/sangue | pt_BR |
DeCS | Doenças Endêmicas | pt_BR |
DeCS | Infecções por Herpesviridae/etnologia | pt_BR |
DeCS | Herpesvirus Humano 8/imunologia | pt_BR |
DeCS | Índios Sul-Americanos | pt_BR |
DeCS | Adolescente | pt_BR |
DeCS | Adulto | pt_BR |
DeCS | Distribuição por Idade | pt_BR |
DeCS | Antígenos Virais/imunologia | pt_BR |
DeCS | Brasil/epidemiologia | pt_BR |
DeCS | Criança | pt_BR |
DeCS | Pré-Escolar | pt_BR |
DeCS | Grupos Étnicos | pt_BR |
DeCS | Feminino | pt_BR |
DeCS | Infecções por Herpesviridae/virologia | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Lactente | pt_BR |
DeCS | Masculino | pt_BR |
DeCS | Meia-Idade | pt_BR |
DeCS | Estudos Soroepidemiológicos | pt_BR |
DeCS | Distribuição por Sexo | pt_BR |