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https://www.arca.fiocruz.br/handle/icict/8768
CLUSTERING OF HTLV-1 ASSOCIATED MYELOPATHY/TROPICAL SPASTIC PARAPARESIS (HAM/TSP) AND INFECTIVE DERMATITIS ASSOCIATED WITH HTLV-1 (IDH) IN SALVADOR, BAHIA, BRAZIL.
Clustering of HTLV-1-associated diseases
HTLV-1 associated myelopathy/tropical spastic paraparesis
Infective dermatitis associated with HTLV-1
HTLV-1 vertical transmission
Dermatite/virologia
Vírus 1 Linfotrópico T Humano/isolamento & purificação
Paraparesia Espástica Tropical/epidemiologia
Paraparesia Espástica Tropical/virologia
Adolescente
Adulto
Brasil/epidemiologia
Criança
Pré-Escolar
Análise por Conglomerados
Feminino
Humanos
Lactente
Masculino
Meia-Idade
Author
Affilliation
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Pathology. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Pathology. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil / National Institute of Science and Technology of Tropical Diseases. Brazil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Pathology. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Pathology. Salvador, BA, Brasil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Internal Medicine. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil / National Institute of Science and Technology of Tropical Diseases. Brazil
Federal University of Bahia. Professor Edgard Santos Teaching Hospital. Department of Pathology. Salvador, BA, Brasil
Abstract
Fifteen families with clustering of infective dermatitis associated with HTLV-1 (IDH) and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) were observed among 28 families of IDH index cases, 93% of them occurring in two generations. With the exception of two mothers of children with IDH, all the mothers with HAM/TSP had at least one child with HAM/TSP. This is the first report of such clustering involving many families.
Keywords
HTLV-1 infectionClustering of HTLV-1-associated diseases
HTLV-1 associated myelopathy/tropical spastic paraparesis
Infective dermatitis associated with HTLV-1
HTLV-1 vertical transmission
DeCS
Dermatite/epidemiologiaDermatite/virologia
Vírus 1 Linfotrópico T Humano/isolamento & purificação
Paraparesia Espástica Tropical/epidemiologia
Paraparesia Espástica Tropical/virologia
Adolescente
Adulto
Brasil/epidemiologia
Criança
Pré-Escolar
Análise por Conglomerados
Feminino
Humanos
Lactente
Masculino
Meia-Idade
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