| Author | Moreira, Luciano Andrade | |
| Author | Ye, Yixin H. | |
| Author | Turner, Karly | |
| Author | Eyles, Darryl W. | |
| Author | McGraw, Elizabeth A. | |
| Author | O’Neill, Scott L. | |
| Access date | 2014-11-26T17:23:19Z | |
| Available date | 2014-11-26T17:23:19Z | |
| Document date | 2011 | |
| Citation | MOREIRA, Luciano Andrade et al. The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti. Parasites & Vectors, v. 4, p. 1-5, 2011. | pt_BR |
| ISSN | 1756-3305 | |
| URI | https://www.arca.fiocruz.br/handle/icict/8978 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | pt_BR |
| Title | The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1186/1756-3305-4-28 | |
| Abstract | Wolbachia is an intracellular bacterium that has been stably transinfected into the mosquito vector of dengue, Aedes aegypti. This inherited infection causes a range of metabolic and phenotypic alterations in the mosquito, which might be related to neuronal abnormalities. In order to determine if these alterations were caused by the manipulation of neuroamines by this bacterium, we studied the expression of genes involved in the dopamine biosynthetic pathway and also measured the amount of dopamine in infected and uninfected mosquitoes of different ages. Wolbachia-infected mosquitoes exhibit greater expression of some genes related to the melanization pathway, but not for those directly linked to dopamine production. Although dopamine levels were higher in Wolbachia-positive mosquitoes this was not consistent across all insect ages nor was it related to the previously described Wolbachia induced “bendy” and “shaky” phenotypes. | pt_BR |
| Affilliation | The University of Queensland. School of Biological Sciences. Brisbane, Australia / Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | The University of Queensland. School of Biological Sciences. Brisbane, Australia. | pt_BR |
| Affilliation | University of Queensland. Queensland Brain Institute. Brisbane, Australia. | pt_BR |
| Affilliation | University of Queensland. Queensland Brain Institute. Brisbane, Australia. | pt_BR |
| Affilliation | The University of Queensland. School of Biological Sciences. Brisbane, Australia. | pt_BR |
| Affilliation | The University of Queensland. School of Biological Sciences. Brisbane, Australia. | pt_BR |
| Subject | Aedes/chemistry | pt_BR |
| Subject | Biosynthetic Pathways | pt_BR |
| Subject | Gene Expression Profiling | pt_BR |
| Subject | Wolbachia/pathogenicity | pt_BR |
