| Author | Giannella-Neto, Antonio | |
| Author | Ribeiro, Gabriel C. da Motta | |
| Author | Santos, Edil L. | |
| Author | Soares, João H. N. | |
| Author | Nunes, Marcelo V. Leão | |
| Author | Jandre, Frederico C. | |
| Access date | 2015-02-10T15:07:25Z | |
| Available date | 2015-02-10T15:07:25Z | |
| Document date | 2010 | |
| Citation | GIANNELLA-NETO, Antonio. et al. Control of positive end-expiratory pressure (PEEP) for small animal ventilators. Biomed. eng. online., London, v . 9, n. 36, 2010. | pt_BR |
| ISSN | 1475-925X | |
| URI | https://www.arca.fiocruz.br/handle/icict/9473 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | pt_BR |
| Title | Control of positive end-expiratory pressure (PEEP) for small animal ventilators | pt_BR |
| Type | Article | pt_BR |
| Abstract | Background:The positive end-expiratory pressure (PEEP) for the mechanical
ventilation of small animals is frequently obtained with water seals or by using
ventilators developed for human use. An alternative mechanism is the use of an on-off expiratory valve closing at the moment when the alveolar pressure is equal to
the target PEEP. In this paper, a novel PEEP controller (PEEP-new) and the PEEP
system of a commercial small-animal ventilator, both based on switching an on-off
valve, are evaluated.
Methods:The proposed PEEP controller is a discrete integrator monitoring the error
between the target PEEP and the airways opening pressure prior to the onset of an
inspiratory cycle. In vitro as well as in vivo experiments with rats were carried out
and the PEEP accuracy, settling time and under/overshoot were considered as a
measure of performance.
Results:The commercial PEEP controller did not pass the tests since it ignores the
airways resistive pressure drop, resulting in a PEEP 5 cmH2
O greater than the target
in most conditions. The PEEP-new presented steady-state errors smaller than 0.5
cmH2O, with settling times below 10 s and under/overshoot smaller than 2 cmH2
O.
Conclusion:The PEEP-new presented acceptable performance, considering accuracy
and temporal response. This novel PEEP generator may prove useful in many
applications for small animal ventilators. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Água | pt_BR |
