| Author | Passini Junior, Renato | |
| Author | Cecatti, Jose G. | |
| Author | Lajos, Giuliane J. | |
| Author | Tedesco, Ricardo P. | |
| Author | Nomura, Marcelo L. | |
| Author | Dias, Tabata Z. | |
| Author | Haddad, Samira M. | |
| Author | Rehder, Patricia M. | |
| Author | Pacagnella, Rodolfo C. | |
| Author | Costa, Maria L. | |
| Author | Sousa, Maria H. | |
| Access date | 2015-03-04T16:42:56Z | |
| Available date | 2015-03-04T16:42:56Z | |
| Document date | 2014 | |
| Citation | PASSINI JUNIOR, Renato. et al. Brazilian multicentre study on preterm birth (EMIP): prevalence and factors associated with spontaneous preterm birth. PLos ONE., San Francisco, v. 9, n. 10, 2014. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/9619 | |
| Language | eng | pt_BR |
| Publisher | Public Library of Science | pt_BR |
| Rights | open access | |
| Title | Brazilian multicentre study on preterm birth (EMIP): prevalence and factors associated with spontaneous preterm birth | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1371/journal.pone.0109069 | |
| Abstract | Background:Preterm birth rate is increasing and is currently a worldwide concern. The purpose of this study was to
estimate the prevalence of preterm birth in a sample of health facilities in Brazil and to identify the main risk factors
associated with spontaneous preterm births.
Methods and Findings:This was a multicentre cross sectional study on preterm births in 20 referral obstetric hospitals with
a case-control component to identify factors associated with spontaneous preterm birth. Surveillance was implemented at
all centres to identify preterm births. For eligible consenting women, data were collected through a post-delivery
questionnaire completed with information from all mother-newborn medical records until death or discharge or at a
maximum of 60 days post-delivery, whichever came first. The risk of spontaneous preterm birth was estimated with OR and
95%CI for several predictors. A non-conditional logistic regression analysis was then performed to identify independently
associated factors. The overall prevalence of preterm birth was 12.3%. Among them, 64.6% were spontaneous and 35.4%
therapeutic. In the case-control component, 2,682 spontaneous preterm births were compared to a sample of 1,146 term
births. Multivariate analyses identified the following as risk factors for spontaneous preterm birth among women with at
least one previous birth: a previous preterm birth (OR
adj= 3.19, 2.30–4.43), multiple pregnancy (ORadj
= 29.06, 8.43–100.2),
cervical insufficiency (ORadj= 2.93, 1.07–8.05), foetal malformation (ORadj= 2.63, 1.43–4.85), polyhydramnios (ORadj
= 2.30,
1.17–4.54), vaginal bleeding (ORadj= 2.16, 1.50–3.11), and previous abortion (ORadj= 1.39, 1.08–1.78). High BMI (ORadj
= 0.94,
0.91–0.97) and weight gain during gestation (ORadj
= 0.92, 0.89–0.95) were found to be protective factors.
Conclusions:The preterm birth rate in these health facilities in Brazil is high and spontaneous preterm births account for
two thirds of them. A better understanding of the factors associated with spontaneous preterm birth is of utmost
importance for planning effective measures to reduce the burden of its increasing rates. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. / Centro de Estudos em Saúde Reprodutiva de Campinas. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. / Faculdade de Medicina de Jundiaí. Jundiaí, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Universidade de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil. | pt_BR |
| Affilliation | Centro de Estudos em Saúde Reprodutiva de Campinas. Campinas, SP, Brasil. | pt_BR |
| DeCS | Coeficiente de Natalidade | pt_BR |
| DeCS | Prematuro | pt_BR |
| DeCS | Trabalho de Parto Prematuro | pt_BR |
| DeCS | Recém-Nascido | pt_BR |
