| Author | Barth, Ortrud Monika | |
| Author | Schatzmayr, Hermann Gonçalves | |
| Author | Gonçalves, Márcia Cristina Rosa | |
| Author | Barreto-Vieira, Débora Ferreira | |
| Author | Fernandes, Jorlan | |
| Author | Lima, Monique Queiroz | |
| Author | Oliveira, Renata Carvalho de | |
| Author | Lemos, Elba Regina Sampaio de | |
| Access date | 2015-04-06T17:18:22Z | |
| Available date | 2015-04-06T17:18:22Z | |
| Document date | 2014 | |
| Citation | BARTH, O. M.; et al. Antibodies anti-orthopoxvirus in healthy workers who handle animals and in patients with cutaneous lesions compatible with poxvirus infection in the state of rio de janeiro, Brazil. Virus Reviews and Research, v.19, p. 4-8,2014. | pt_BR |
| ISSN | 15192563 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/9899 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Virologia | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Subject in Portuguese | Orthopoxvirus | pt_BR |
| Title | Antibodies anti-Orthopoxvirus in healthy workers who handle animals and in patients with cutaneous lesions compatible with poxvirus infection in the state of Rio de Janeiro, Brazil. | pt_BR |
| Type | Article | |
| Director | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Abstract | Th e incidence of poxvirosis, a zoonosis caused by viruses of the family Poxviridae, has increased over the past two
decades in Brazil. Th e important features of the Orthopoxvirus infection include rapid spread, occurrence restricted
to lactating cows, lack of hygiene, person-to-person spread, and occurrence at properties where milking is conducted.
We detected the presence of vaccinia virus antibodies, specifi cally for Cantagalo virus, in samples from two distinct
populations from the state of Rio de Janeiro: (i) healthy professionals who live in the State of Rio de Janeiro and handle
animals and (ii) in patients with cutaneous lesions compatible with poxvirosis. Th e plaque reduction neutralisation
test (PRNT) was used. Of the 136 samples from the group of healthy professionals, 12 displayed seroreactivity with
titres lower than or equal to 1/10. Anti-poxvirus antibodies were detected in 68.3% of samples of patients suspected to
be infected with poxvirus (28/41). Th erefore, the plaque reduction neutralisation test constitutes a sensitive assay that
can be more commonly used for diagnosis. Furthermore, professionals who handle animals should be included as an
occupational risk group in areas with confi rmed human poxvirus cases. | en |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | |
| Subject | Antibodies | en |
| Subject | Health workers | en |
| Subject | Patients | en |
