| Author | Souza, W.M. | |
| Author | Bello, G. | |
| Author | Amarilla, A. A. | |
| Author | Alfonso, H. L. | |
| Author | Aquino, V. H. | |
| Author | Figueiredo, L. T. M. | |
| Access date | 2015-04-14T12:38:12Z | |
| Available date | 2015-04-14T12:38:12Z | |
| Document date | 2014 | |
| Citation | Souza, W.M. et al. Phylogeography and evolutionary history of rodent-borne hantavirus. Infect Genet Evol., v.21, p.198-204, 2014. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/9978 | |
| Language | por | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | |
| Title | Phylogeography and evolutionary history of rodent-borne hantaviruses | pt_BR |
| Type | Article | |
| Abstract | Hantavirus (Family Bunyaviridae) are mostly associated to rodents and transmitted to man by inhalation
of aerosolized infected excreta of these animals. The human infection by hantaviruses can lead to severe
diseases such as hemorrhagic fever with renal syndrome (HFRS) in Asia and Europe, and pulmonary syndrome
(HPS) in the Americas. To determine the origin, spreading and evolutionary dynamics of rodentborne
hantaviruses, 190 sequences of nucleoprotein (N) of hantaviruses identified in 30 countries, from
1985 to 2010, were retrieved from the GenBank and analyzed using the BEAST program. Our evolutionary
analysis indicates that current genetic diversity of N gene of rodent-borne hantaviruses probably was
originated around 2000 years ago. Hantavirus harbored by Murinae and Arvicolinae subfamilies, probably,
were originated in Asia 500–700 years ago and later spread toward Siberia, Europe, Africa and North
America. Hantavirus carried by Neotominae subfamily, probably, emerged 500–600 years ago in Central
America and spread toward North America. Finally, hantaviruses associated to Sigmodontinae occurred
in Brazil 400 years ago and were, probably, originated from Neotominae-associated virus from northern
South America. These data offer subsidies to understand the time-scale and worldwide dissemination
dynamics of rodent-borne hantaviruses. | pt_BR |
| Affilliation | Universidade de São Paulo. Escola de Medicina de Ribeirão Preto. Centro de Pesquisa em Virologia. Ribeirão Preto, São Paulo, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, São Paulo, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, São Paulo, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, São Paulo, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Escola de Medicina de Ribeirão Preto. Centro de Pesquisa em Virologia. Ribeirão Preto, São Paulo, Brasil. | pt_BR |
| Subject | Hantavirus | pt_BR |
| Subject | Rodent-borne | pt_BR |
| Subject | Evolution | pt_BR |
| Subject | Phylogeography | pt_BR |
| DeCS | Filogeografia | pt_BR |
| DeCS | Hantavirus | pt_BR |
