Browsing by Subject "Ligands"

Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents

Minu, Maninder et al. | Date Issued: 2016

Discovery of new hydroxyethylamine analogs against 3CLpro protein target of SARS-CoV-2: molecular docking, molecular dynamics simulation, and structure−activity relationship studies

Kumar, Sumit et al. | Date Issued: 2020

Exploring novel antimalarial compounds targeting plasmodium falciparum Enoyl-ACP reductase: computational and experimental insights

Oliveira, George Azevedo Reis de et al. | Date Issued: 2024

Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40)

Rodrigues, Daniel Alencar et al. | Date Issued: 2018

O receptor acoplado à proteína G 40 (GPR40) foi recentemente identificado como um alvo interessante para o tratamento do diabetes tipo 2. O alto nível de expressão nas células beta pancreáticas e a dependência da glicose ...

Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru(II) complexes

Thota, Sreekanth et al. | Date Issued: 2016

Relatamos a síntese de novos compostos de Ru(II) (Ru-1 a Ru-8) contendo ligantes R-pdc, 4-Cl-pbinh (onde R = 4-CF3, 4-F, 4-OH pdc = 3-fenil-5-(1H-pirrol-2-il)-4,5-di-hidro-1H-pirazol-1-carbotioamida, pbinh = fenoxibenzilideno ...