Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/10089
Title: A longitudinal study of Angiostrongylus cantonensis in an urban population of Rattus norvegicus in Brazil: the influences of seasonality and host features on the pattern of infection
Authors: Simões, Raquel O
Maldonado Jr., Arnaldo
Olifiers, Natalie
Garcia, Juberlan S
Bertolino, Ana Valéria F. A
Luque, José L
Affilliation: Universidade Federal Rural do Rio de Janeiro. Curso de Pós-graduação em Ciências Veterinárias. Seropédica, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil
Universidade do Estado do Rio de Janeiro. Faculdade de Formação de Professores. Departamento de Geografia. São Gonçalo, RJ, Brasil.
Universidade Federal Rural do Rio de Janeiro. Departamento de Parasitologia Animal. Seropédica, RJ, Brasil.
Abstract: Background: The nematode Angiostrongylus cantonensis is a zoonotic parasite and the most important cause of eosinophilic meningitis worldwide in humans. In Brazil, this disease has been reported in the states of Espírito Santo and Pernambuco. The parasite has been detected in the naturally infected intermediate host, in the states of Rio de Janeiro, Pernambuco and Santa Catarina. The murid Rattus norvegicus R. rattus were recently reported to be naturally infected in Brazil. In this study, we conducted a two-year investigation of the dissemination pattern of A. cantonensis in R. norvegicus in an urban area of Rio de Janeiro state, Brazil, and examined the influence of seasonality, year, host weight and host gender on parasitological parameters of A. cantonensis in rats. Methods: The study was conducted in an area of Trindade, São Gonçalo municipality, Rio de Janeiro, Brazil. Prevalence of infected rats, intensity and abundance of A. cantonensis were calculated, and generalized linear models were created and compared to verify the contribution of host gender, host weight, year and seasonality to the variations in A. cantonensis abundance and prevalence in rats. Results: The prevalence of A. cantonensis infection was stable during the rainy (71%, CI 58.9- 81.6) and dry seasons (71%, CI 57.9-80.8) and was higher in older rats and in females. Seasonality, host weight (used as a proxy of animal age) and gender were all contributing factors to variation in parasite abundance, with females and heavier (older) animals showing larger abundance of parasites, and extreme values of parasite abundance being more frequent in the dry season. Conclusions: The high prevalence of this parasite throughout the study suggests that its transmission is stable and that conditions are adequate for the spread of the parasite to previously unaffected areas. Dispersion of the parasite to new areas may be mediated by males that tend to have larger dispersal ability, while females may be more important for maintaining the parasite on a local scale due to their higher prevalence and abundance of infection. A multidisciplinary approach considering the ecological distribution of the rats and intermediate hosts, as well as environmental features is required to further understand the dynamics of angiostrongyliasis.
Keywords: Rattus norvegicus
Angiostrongylus cantonensis
Pattern of infection
Brazil
Keywords in spanish: Angiostrongylus cantonensis
Ratas
Brasil
keywords: Ratos
Angiostrongylus cantonensis
Brasil
Issue Date: 2014
Publisher: BioMed Central
Citation: SIMÕES, Raquel O et al. A longitudinal study of Angiostrongylus cantonensis in an urban population of Rattus norvegicus in Brazil: the influences of seasonality and host features on the pattern of infection. Parasites & Vectors, v.7, n.100, 8p, 2014.
DOI: 10.1186/1756-3305-7-100
ISSN: 1756-3305
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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