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EOSINOPHILIC MENINGITIS CAUSED BY ANGIOSTRONGYLUS CANTONENSIS: AN EMERGENT DISEASE IN BRAZIL
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Pontifícia Universidade do Rio Grande do Sul. Faculdade de Biociências. Laboratório de Biologia Parasitária. Instituto de Pesquisas Biomédicas. laboratório de Parasitologia Molecular. Porto Alegre, RS, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Malacologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Malacologia. Rio de Janeiro, RJ, Brasil.
Khon Kaen University. Faculty of Medicine. Center for Emerging Infectious Diseases. Department of Medicine. Khon Kaen, Thailand.
Pontifícia Universidade do Rio Grande do Sul. Faculdade de Biociências. Laboratório de Biologia Parasitária. Instituto de Pesquisas Biomédicas. laboratório de Parasitologia Molecular. Porto Alegre, RS, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Malacologia. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Malacologia. Rio de Janeiro, RJ, Brasil.
Khon Kaen University. Faculty of Medicine. Center for Emerging Infectious Diseases. Department of Medicine. Khon Kaen, Thailand.
Pontifícia Universidade do Rio Grande do Sul. Faculdade de Biociências. Laboratório de Biologia Parasitária. Instituto de Pesquisas Biomédicas. laboratório de Parasitologia Molecular. Porto Alegre, RS, Brasil.
Abstract
Eosinophilic meningitis (EoM) is an acute disease that affects the central nervous system. It is primarily caused
by infection with the nematode Angiostrongylus cantonensis. This infection was previously restricted to certain
Asian countries and the Pacific Islands, but it was first reported in Brazil in 2007. Since then, intermediate and
definitive hosts infected with A. cantonensis have been identified within the urban areas of many states in Brazil, including
those in the northern, northeastern, southeastern and southern regions. The goals of this review are to draw
the attention of the medical community and health centres to the emergence of EoM in Brazil, to compile information
about several aspects of the human infection and mode of transmission and to provide a short protocol of procedures
for the diagnosis of this disease.
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