Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/10609
Title: Effectiveness of Laser Doppler Perfusion Monitoring in the Assessment of Microvascular Function in Patients Undergoing On-Pump Coronary Artery Bypass Grafting
Authors: Salgado, Maria A. M
Salgado Filho, Marcelo F
Brito, José O. Reis
Lessa, Marcos A
Tibiriça, Eduardo
Affilliation: Ministério da Saúde. Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil.
Ministério da Saúde. Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil.
Ministério da Saúde. Instituto Nacional de Cardiologia. Rio de janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ, Brasil.
Ministério da Saúde. Instituto Nacional de Cardiologia. Rio de janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ, Brasil.
Abstract: Objectives: To evaluate the effectiveness of single-point laser Doppler perfusion monitoring (LDPM) in the assessment of microvascular reactivity in the skin during cardiopulmonary bypass (CPB). Design: Cross-sectional observational study. Setting: Government-affiliated teaching hospital. Participants: Twenty male patients aged 60 2 years who underwent coronary artery bypass grafting under CPB. Interventions: The authors assessed the endotheliumdependent vasodilation of the skin microcirculation at the forehead and forearm using LDPM coupled with thermal hyperemia. This measurement was performed before and after the induction of anesthesia, during and after CPB, and 24 h after the end of the surgical procedure. Results: The basal values of microvascular flow before the induction of anesthesia were significantly higher in the skin of the forehead compared with that of the forearm. There were no significant alterations in microvascular reactivity throughout the recording periods for both recording sites, as assessed by the vasodilation range expressed as cutaneous vascular conductance (arbitrary perfusion units / mean arterial pressure). Conclusions: Using LDPM, the authors showed that the microcirculatory bed of the skin of the forehead, which is readily accessible during cardiac surgery, is a suitable model for the study of microvascular reactivity and tissue perfusion in cardiovascular surgical procedures using CPB. This technique could, thus, be suitable for evaluating the effects of drugs or technical procedures on tissue perfusion during cardiac surgery under cardiopulmonary bypass.
Keywords: Laser Doppler
Skin microvascular reactivity
Cardiopulmonary bypass
Perfusion monitoring
DeCS: Ponte Cardiopulmonar
Issue Date: 2014
Publisher: Elsevier
Citation: SALGADO, Maria A. M. et al. Effectiveness of Laser Doppler Perfusion Monitoring in the Assessment of Microvascular Function in Patients Undergoing On-Pump Coronary Artery Bypass Grafting. Journal of Cardiothoracic and Vascular Anesthesia, v.28, n.5, p.1211–1216, oct. 2014.
DOI: 10.1053/j.jvca.2014.03.003
ISSN: 1053-0770
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
marcos_lessaetal_IOC_2014.pdf403.3 kBAdobe PDF    Request a copy


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.