| Author | Daliry, Anissa | |
| Author | Caldas, Ivo Santana | |
| Author | Diniz, Livia de Figueiredo | |
| Author | Torres, Rosália Morais | |
| Author | Talvani, André | |
| Author | Bahia, Maria Therezinha | |
| Author | Carvalho, Antônio Carlos Campos de | |
| Access date | 2015-06-01T19:34:23Z | |
| Available date | 2015-06-01T19:34:23Z | |
| Document date | 2014 | |
| Citation | DALIRY, Anissa et al. Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole. International Journal of Cardiology, v.170, n.3, p.e66–e67, 2014. | pt_BR |
| ISSN | 0167-5273 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/10612 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | |
| Title | Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.ijcard.2013.11.022 | pt_BR |
| Abstract | Chronic chagasic cardiomyopathy (CCC) is a public health problem still without a defined physiopathology. It results from a chronic infection by Trypanosoma cruzi and is characterized by irreversible lesions to the heart. The contribution of autoimmune processes to cardiac dysfunctions observed in CCC has been hypothesized by several authors [1–3]. Those studies demonstrated the presence of IgG components in sera of patients with CCC and dilated cardiomyopathy interacting with cardiac β1-adrenergic (anti-β1-AR) and muscarinic membrane receptors (anti-M2-CR) [3]. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Typanosoma cruzi | pt_BR |
| Subject | Cadiomiopathy | pt_BR |
| Subject | Autoantibodies | pt_BR |
| Subject | Beta-adrenergic receptor | pt_BR |
| Subject | Muscarinic cholinergic receptor | pt_BR |
| DeCS | Cardiomiopatia Chagásica | pt_BR |
| DeCS | Autoanticorpos | pt_BR |
| DeCS | Trypanosoma cruzi | pt_BR |
