Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/11513
Title: Chikungunya virus transmission potential by local Aedes mosquitoes in the Americas and Europe
Authors: Vega-Rúa, Anubis
Oliveira, Ricardo Lourenço de
Mousson, Laurence
Vazeille, Marie
Fuchs, Sappho
Yébakima, André
Gustave, Joel
Girod, Romain
Dusfour, Isabelle
Leparc-Goffart, Isabelle
Vanlandingham, Dana L.
Huang, Yan-Jang S.
Lounibos, L. Philip
Mohamed Ali, Souand
Nougairede, Antoine
Lamballerie, Xavier de
Failloux, Anna-Bella
Affilliation: Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France / Sorbonne Universités. Université Pierre et Marie Curie-Paris 6. Institut de Formation Doctorale (IFD). Paris, France.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil.
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France.
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France.
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France.
Centre de Démoustication/Conseil Général de La Martinique.Fort-de-France, Martinique, France.
Agence Régionale de Danté (ARS) Guadeloupe. Saint-Martin et Saint-Barthélemy. Pole de Santé Publique. Gourbeyre, Guadeloupe, France.
Agence Régionale de Danté (ARS) Guadeloupe. Saint-Martin et Saint-Barthélemy. Pole de Santé Publique. Gourbeyre, Guadeloupe, France.
Hôpital d’Instruction des Armées Laveran. Institut de Recherche Biomédicale des Armées. Centre National de Référence (CNR) des Arbovirus. Marseille, France.
Kansas State University. College of Veterinary Medicine. Department of Diagnostic Medicine and Pathobiology. Biosecurity Research Institute. Manhattan, Kansas, USA /
Kansas State University. Biosecurity Research Institute. Manhattna, Kansas, USA.
University of Florida. Florida Medical Entomology Laboratory. Vero Beach, Florida, USA.
Aix Marseille Université. IRD French Institute of Research for Development. EHESP French School of Public Health. EPV UMR_D 190 ‘Emergence des Pathologies Virales’. Marseille, France / IHU Méditerranée Infection. APHM Public Hospitals of Marseille. Marseille, France.
Aix Marseille Université. IRD French Institute of Research for Development. EHESP French School of Public Health. EPV UMR_D 190 ‘Emergence des Pathologies Virales’. Marseille, France / IHU Méditerranée Infection. APHM Public Hospitals of Marseille. Marseille, France.
Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, Paris, France
Abstract: Background Chikungunya virus (CHIKV), mainly transmitted in urban areas by the mosquitoes Aedes aegypti and Aedes albopictus, constitutes a major public health problem. In late 2013, CHIKV emerged on Saint-Martin Island in the Caribbean and spread throughout the region reaching more than 40 countries. Thus far, Ae. aegypti mosquitoes have been implicated as the sole vector in the outbreaks, leading to the hypothesis that CHIKV spread could be limited only to regions where this mosquito species is dominant.Methodology/Principal Findings We determined the ability of local populations of Ae. aegypti and Ae. albopictus from the Americas and Europe to transmit the CHIKV strain of the Asian genotype isolated from Saint-Martin Island (CHIKV_SM) during the recent epidemic, and an East-Central-South African (ECSA) genotype CHIKV strain isolated from La Réunion Island (CHIKV_LR) as a well-characterized control virus. We also evaluated the effect of temperature on transmission of CHIKV_SM by European Ae. albopictus.We found that (i) Aedes aegypti from Saint-Martin Island transmit CHIKV_SM and CHIKV_LR with similar efficiency, (ii) Ae. aegypti from the Americas display similar transmission efficiency for CHIKV_SM, (iii) American and European populations of the alternative vector species Ae. albopictus were as competent as Ae. aegypti populations with respect to transmission of CHIKV_SM and (iv) exposure of European Ae. albopictus to low temperatures (20°C) significantly reduced the transmission potential for CHIKV_SM.Conclusions/Significance CHIKV strains belonging to the ECSA genotype could also have initiated local transmission in the new world. Additionally, the ongoing CHIKV outbreak in the Americas could potentially spread throughout Ae. aegypti- and Ae. albopictus-infested regions of the Americas with possible imported cases of CHIKV to Ae. albopictus-infested regions in Europe. Colder temperatures may decrease the local transmission of CHIKV_SM by European Ae. albopictus, potentially explaining the lack of autochthonous transmission of CHIKV_SM in Europe despite the hundreds of imported CHIKV cases returning from the Caribbean.
Keywords: Chikungunya Virus
Aedes Mosquitoes
Americas
Europe
Transmission
keywords: Transmissão
Américas
Europa
Mosquitos
DeCS: Vírus Chikungunya
Aedes
Issue Date: 2015
Publisher: Plos One
Citation: VEGA-RÚA, Anubis; et al. Chikungunya virus transmission potential by local Aedes mosquitoes in the Americas and Europe. PLoS Negl Trop Dis., v.9, n.5: e0003780, 2015.
DOI: 10.1371/journal.pntd.0003780
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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