Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/11818
Title: Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus
Authors: Oliveira, Ricardo Lourenço de
Rua, Anubis Vega
Vezzani, Dario
Willat, Gabriela
Vazeille, Marie
Mousson, Laurence
Failloux, Anna Bella
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil / Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France.
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France
Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (CONICET). Buenos Aires, Argentina.
Ministerio de Salud Pública. Dirección General de la Salud. Unidad de Zoonosis y Vectores. Montevideo, Uruguay.
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France
Institut Pasteur. Department of Virology, Arboviruses and Insect Vectors. Paris, France
Abstract: Background: Aedes aegypti is extensively spread throughout South America where it has been responsible for large dengue epidemics during the last decades. Intriguingly, dengue transmission has not been reported in Uruguay and is essentially prevalent in subtropical northern Argentina which borders Uruguay. Methods: We assessed vector competence for dengue virus (DENV) of Ae. aegypti populations collected in subtropical Argentina (Corrientes) as well as temperate Uruguay (Salto) and Argentina (Buenos Aires) in 2012 using experimental oral infections with DENV-2. Mosquitoes were incubated at 28°C and examined at 14 and 21 days p.i. to access viral dissemination and transmission. Batches of the Buenos Aires mosquitoes were also incubated at 15°C and 20°C. Results: Although mosquitoes from temperate Uruguay and Argentina were competent to transmit DENV, those from subtropical Argentina were more susceptible, displaying the highest virus titters in the head and presenting the highest dissemination of infection and transmission efficiency rates when incubated at 28°C. Interestingly, infectious viral particles could be detected in saliva of mosquitoes from Buenos Aires exposed to 15°C and 20°C. Conclusions: There is a potential risk of establishing DENV transmission in Uruguay and for the spread of dengue outbreaks to other parts of subtropical and temperate Argentina, notably during spring and summer periods.
Keywords: Vector competence
Experimental infections
Argentina
Uruguay
Dengue
DeCS: Aedes
Dengue
Issue Date: 2013
Publisher: BioMed Central
Citation: OLIVEIRA, Ricardo Lourenço de; et al. Aedes aegypti from temperate regions of South America are highly competent to transmit dengue virus. BMC Infectious Diseases, v.13, n.610, 8p, 2013.
DOI: 10.1186/1471-2334-13-610
ISSN: 1471-2334
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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