Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/12239
Title: An overview of malaria transmission from the perspective of Amazon Anopheles vectors
Authors: Pimenta, Paulo F. P.
Orfano, Alessandra S.
Bahia, Ana C.
Duarte, Ana P. M.
Rios-Velásquez, Claudia M.
Melo, Fabrício F.
Pessoa, Felipe A. C.
Oliveira, Giselle A.
Campos, Keillen M, M.
Villegas, Luis Martínez
Rodrigues, Nilton Barnabé
Pimenta, Rafael Nacif
Simões, Rejane C.
Monteiro, Wuelton M.
Amino, Rogerio
Traub-Cseko, Yara M.
Lima, José B. P.
Barbosa, Maria G. V.
Lacerda, Marcus V. G.
Tadei, Wanderli P.
Secundino, Nágila F. C.
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil / Fundação de Medicina Tropical Dr Heitor Vieira Dourado. Manaus, AM, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil
Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil..
Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil.
Fundação de Medicina Tropical Dr Heitor Vieira Dourado. Manaus, AM, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil.
Instituto Nacional de Pesquisas da Amazônia. Manaus, AM, Brasil.
Fundação de Medicina Tropical Dr Heitor Vieira Dourado. Manaus, AM, Brasil.
Institut Pasteur. Unité de Biologie et Génétique du Paludisme. Paris, France.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, AM, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, AM, Brasil.
Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, AM, Brasil / stituto Leônidas e Maria Deane-Fiocruz, Manaus, AM, Brasil .
Instituto Nacional de Pesquisas da Amazônia. Manaus, AM, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Minas Gerais, MG, Brasil.
Abstract: In the Americas, areas with a high risk of malaria transmission are mainly located in the Amazon Forest, which extends across nine countries. One keystone step to understanding the Plasmodium life cycle in Anopheles species from the Amazon Region is to obtain experimentally infected mosquito vectors. Several attempts to colonise Anopheles species have been conducted, but with only short-lived success or no success at all. In this review, we review the literature on malaria transmission from the perspective of its Amazon vectors. Currently, it is possible to develop experimental Plasmodium vivax infection of the colonised and field-captured vectors in laboratories located close to Amazonian endemic areas. We are also reviewing studies related to the immune response to P. vivax infection of Anopheles aquasalis, a coastal mosquito species. Finally, we discuss the importance of the modulation of Plasmodium infection by the vector microbiota and also consider the anopheline genomes. The establishment of experimental mosquito infections with Plasmodium falciparum, Plasmodium yoelii and Plasmodium berghei parasites that could provide interesting models for studying malaria in the Amazonian scenario is important. Understanding the molecular mechanisms involved in the development of the parasites in New World vectors is crucial in order to better determine the interaction process and vectorial competence.
Keywords: Anopheles
Plasmodium
Transmission
Amazon vectors
keywords: Transmissão
Amazônia
DeCS: Plasmodium
Anopheles
Malária
Issue Date: 2015
Publisher: Fundação Oswaldo Cruz
Citation: PIMENTA, Paulo F. P. et al. An overview of malaria transmission from the perspective of Amazon Anopheles vectors. Mem Inst Oswaldo Cruz, v.110, n.1, p. 23-47, Feb. 2015.
DOI: 10.1590/0074-02760140266
ISSN: 0074-0276
Copyright: open access
Appears in Collections:MG - IRR - Artigos de Periódicos
AM - ILMD - Artigos de Periódicos
IOC - Artigos de Periódicos

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