Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/12292
COMPOSICIÓN FARMACÉUTICA DE DIDANOSINA
Blanver Farmoquímica Ltda. Brasil.
PCT
Europa
Brasil
Inventor(s)
Affilliation
Blanver Farmoquímica Ltda. Cotia, SP, Brasil
Blanver Farmoquímica Ltda. Cotia, SP, Brasil
Blanver Farmoquímica Ltda. Cotia, SP, Brasil
Applicant
Fundação Oswaldo Cruz. Brasil.Blanver Farmoquímica Ltda. Brasil.
Filling number
ES200703002
Filling date
2007-11-14
Patent number
ES2331501 A1
Issue date
2010-01-05
Date of Patent:
2010-10-21
xmlui.dri2xhtml.METS-1.0.paisesconcessao
EspanhaAbstract
The present invention relates to a new solid pharmaceutical composition of didanosine comprising didanosine crystals with an average particle size comprised between 50 and 500 microns, coated by a layer of an enteric coating. The pharmaceutical composition of the invention can be prepared by means of a simple process, which comprises coating the didanosine crystals with an enteric layer. Said composition has a good stability of the active ingredient, as well as a suitable release in the conditions present in the upper part of the gastrointestinal tract. It also relates to the use of said composition for preparing solid dosage forms of didanosine for their oral administration. The invention also relates to tablets and to hard gelatin capsules containing said composition.
IPC number
A61K 9/16A61K 9/50A61K 31/505
Filling country
EspanhaPCT
Europa
Brasil
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