Author | Maleck, Marise | |
Author | Santos, Fernanda Cristina Carvalho dos | |
Author | Serdeiro, Michele Teixeira | |
Author | Guimarães, Anthony Érico | |
Author | Ferreira, Bruna | |
Author | Gunaydin, Keriman | |
Author | Almeida, Ana Paula de | |
Access date | 2016-01-12T12:40:37Z | |
Available date | 2016-01-12T12:40:37Z | |
Document date | 2013 | |
Citation | MALEK, Marise; et al. Khellin: A furanochromone with toxicity against Oncopeltus fasciatus (Hemiptera) and Aedes aegypti (Diptera). Journal of Natural Pharmaceuticals, v.4, n.1, p.32-36, Jan. / June 2013. | pt_BR |
ISSN | 2229-5119 | |
URI | https://www.arca.fiocruz.br/handle/icict/12516 | |
Language | eng | pt_BR |
Publisher | Pharmacognosy Network Worldwide | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Produtos naturais | pt_BR |
Subject in Portuguese | Larvicida | pt_BR |
Title | Khellin: A furanochromone with toxicity against Oncopeltus fasciatus (Hemiptera) and Aedes aegypti (Diptera) | pt_BR |
Type | Article | pt_BR |
DOI | 10.4103/2229-5119.110348 | |
Abstract | Natural products isolated from plants may be an alternative source of larvicidal and insecticide activity. Khellin
is a natural furanochromone isolated from fruits of Ammi visnaga (L.) Lam. (Umbelliferae family), which grows
extensively in the Mediterranean region. This substance shows several types of biological activity, such as in
vitro cytotoxicity, antispasmodic action, and phototherapeutic potential. Dengue is a tropical disease caused
by an arbovirus transmitted by Aedes aegypti; the milkweed bug, Oncopeltus fasciatus, is a phytophagous
Hemiptera and a Phytomonas vector. Our main goal was to evaluate the toxicity of khellin in relation to the
nymphs of O. fasciatus (Hemiptera) and larvae of A. aegypti (Diptera). To the best of our knowledge, this is
the fi rst report concerning furanochromone bioactivity against insect vectors for human disease. | pt_BR |
Affilliation | Universidade Severino Sombra (USS). Laboratório de Insetos Vetores/CECETEN. Vassouras, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Díptera. Rio de Janeiro, RJ, Brasil / Universidade do Porto. Centro de Química Medicina - CEQUIMED-UP. Porto, Portugal. | pt_BR |
Affilliation | Universidade Severino Sombra (USS). Laboratório de Insetos Vetores/CECETEN. Vassouras, RJ, Brasil. | pt_BR |
Affilliation | Universidade Severino Sombra (USS). Laboratório de Insetos Vetores/CECETEN. Vassouras, RJ, Brasil / Universidade Severino Sombra (USS). Mestrado Profissional em Ciências Ambientais. Vassouras, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Díptera. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Severino Sombra (USS). Laboratório de Insetos Vetores/CECETEN. Vassouras, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Díptera. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Istanbul Üniversity. Science Faculty. Molecular Biyoloji and Genetics. Turkey. | pt_BR |
Affilliation | Universidade do Porto. Faculdade de Farmácia. Departamento de Ciências Químicas. Laboratório de Química Orgânica e Farmacêutica. Porto, Portugal / Universidade do Porto. Centro de Química Medicina - CEQUIMED-UP. Porto, Portugal / Universidade Severino Sombra (USS). Mestrado Profissional em Ciências Ambientais. Vassouras, RJ, Brasil. | pt_BR |
Subject | Ammi visnaga (L.) | pt_BR |
Subject | Bioactivity | pt_BR |
Subject | Culicidae | pt_BR |
Subject | Hemiptera | pt_BR |
Subject | Larvicidal | pt_BR |
Subject | Natural products | pt_BR |
DeCS | Hemípteros | pt_BR |
DeCS | Culicidae | pt_BR |
e-ISSN | 2229-7715 | |