Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/12721
Title: Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment
Authors: Porrás, Analía I.
Yadon, Zaida E.
Altcheh, Jaime
Britto, Constança
Chaves, Gabriela C.
Flevaud, Laurence
Martins Filho, Olindo Assis
Ribeiro, Isabela
Schijman, Alejandro G.
Yasuda, Maria Aparecida Shikanai
Sosa-Estani, Sergio
Stobbaerts, Eric
Zicker, Fabio
Affilliation: World Health Organization. Pan American Health Organization. Washington, D.C., United States of America
World Health Organization. Pan American Health Organization. Washington, D.C., United States of America
Hospital de Niños Ricardo Gutiérrez. Servicio de Parasitología y Chagas. Buenos Aires, Argentina
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saude Publica Sergio Arouca. Rio de Janeiro, RJ, Brasil
Médecins Sans Frontières. Barcelona-Athens, Barcelona, Spain
Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Laboratorio de Biomarcados de Monitoramento e Diagnostico. Belo Horizonte, MG, Brasil
Drugs for Neglected Diseases initiative. Latin America Regional Office. Rio de Janeiro, RJ. Brasil
Instituto de Investigaciones en Ingeniería Genética y Biología Molecular Dr Hector Torres. Laboratorio de Biología Molecular de la Enfermedad de Chagas. Buenos Aires, Argentina
Universidade de São Paulo. Faculdade de Medicina. Departamento de Doenças Infecciosas e Parasitarias. Sao Paulo, SP, Brasil
Ministerio de Salud. Instituto Nacional de Parasitología, Dr. Mario Fatala Chaben. Buenos Aires, Argentina
Drugs for Neglected Diseases initiative. Latin America Regional Office. Rio de Janeiro, RJ. Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Centro de Desenvolvimento Tecnologico em Saude. Rio de Janeiro, RJ, Brasil
Abstract: A first and critical step to address the research and development gap for Chagas disease is to establish a consensus on the desirable product profiles in different conditions of use. To foster and inform the development of these much needed tools, the Pan American Health Organization (PAHO), in collaboration with DNDi, Médecins sans Frontières (MSF), and the Special Programme for Research and Training in Tropical Diseases (TDR), convened a multidisciplinary group of experts in Rio de Janeiro, Brazil (April 2010), to review the evidence and initiate discussions. The meeting established the basis for the development of target product profiles (TPPs), which are reported in this paper.
Keywords: Chagas disease
Chagas disease/Treatment
Issue Date: 2015
Publisher: Public Library of Science
Citation: PORRÁS, Analía I. et al. Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment. PLOS Neglected Tropical Diseases, 2015, 9(6):e0003697.
DOI: 10.1371/journal.pntd.0003697
ISSN: 1935-2735
Copyright: open access
Appears in Collections:IRR - Artigos de Periódicos



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