| Author | Clemente, Adauto Silva | |
| Author | Diniz, Breno Satler de Oliveira | |
| Author | Nicolato, Rodrigo | |
| Author | Kapczinski, Flavio Pereira | |
| Author | Soares, Jair C. | |
| Author | Firmo, Josélia Oliveira Araújo | |
| Author | Costa, Érico Castro | |
| Access date | 2016-02-17T15:30:07Z | |
| Available date | 2016-02-17T15:30:07Z | |
| Document date | 2015 | |
| Citation | CLEMENTE, Adauto Silva et al. Bipolar disorder prevalence: a systematic review and meta-analysis of the literature. Revista Brasileira de Psiquiatria, v. 37, n. 2, p. 155-161, 2015. | pt_BR |
| ISSN | 1809-452X | |
| URI | https://www.arca.fiocruz.br/handle/icict/12747 | |
| Language | eng | pt_BR |
| Publisher | Associação Brasileira de Psiquiatria | pt_BR |
| Rights | open access | pt_BR |
| Title | Bipolar disorder prevalence: a systematic review and meta-analysis of the literature | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/1516-4446-2012-1693 | |
| Abstract | Objective: Bipolar disorder (BD) is common in clinical psychiatric practice, and several studies have estimated its prevalence to range from 0.5 to 5% in community-based samples. However, no systematic review and meta-analysis of the prevalence of BD type 1 and type 2 has been published in the literature. We carried out a systematic review and meta-analysis of the lifetime and 1-year prevalence of BD type 1 and type 2 and assessed whether the prevalence of BD changed according to the diagnostic criteria adopted (DSM-III, DSM-III-R vs. DSM-IV).
Methods: We searched MEDLINE, Scopus, Web of Science, PsycINFO, and the reference lists of identified studies. The analyses included 25 population- or community-based studies and 276,221 participants.
Results: The pooled lifetime prevalence of BD type 1 was 1.06% (95% confidence interval [95%CI] 0.81-1.31) and that of BD type 2 was 1.57% (95%CI 1.15-1.99). The pooled 1-year prevalence was 0.71% (95%CI 0.56-0.86) for BD type 1 and 0.50% (95%CI 0.35-0.64) for BD type 2. Subgroup analysis showed a significantly higher lifetime prevalence of BD type 1 according to the DSM-IV criteria compared to the DSM-III and DSM-IIIR criteria (p < 0.001).
Conclusion: This meta-analysis confirms that estimates of BD type 1 and type 2 prevalence are low in the general population. The increase in prevalence from DSM-III and DSM-III-R to DSM-IV may reflect different factors, such as minor changes in diagnostic operationalization, use of different assessment instruments, or even a genuine increase in the prevalence of BD. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Saúde Mental.Belo Horizonte, MG, Brasil / Universidade Federal de Minas Gerais. Instituto Nacional de Ciência e Tecnologia de Medicina Molecular. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Saúde Mental.Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre. Instituto Nacional de Ciência e Tecnologia de Medicina Translacional. Laboratório de Psiquiatria Molecular. Porto Alegre, RS, Brasil / University of Texas Health Science Center. Department of Psychiatry and Behavioral Sciences. Center of Excellence on Mood Disorders. Houston, TX, USA. | pt_BR |
| Affilliation | University of Texas Health Science Center. Department of Psychiatry and Behavioral Sciences. Center of Excellence on Mood Disorders. Houston, TX, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil. | pt_BR |
| Subject | Bipolar disorder | pt_BR |
| Subject | Prevalence | pt_BR |
| Subject | Meta-analysis | pt_BR |
| Subject | DSM-III | pt_BR |
| Subject | DSM-III-R | pt_BR |
| Subject | DSM-IV | pt_BR |
