| Author | Jurberg, Arnon Dias | |
| Author | Fontes, Larissa Vasconcelos | |
| Author | Almeida, Vinicius Cotta de | |
| Access date | 2016-02-22T11:51:10Z | |
| Available date | 2016-02-22T11:51:10Z | |
| Document date | 2015 | |
| Citation | JURBERG, Arnon Dias; FONTES, Larissa Vasconcelos; ALMEIDA, Vinícius Cotta de. A tale from TGF-β superfamily for thymus ontogeny and function. Frontiers in Immunology, v.6, Article 442, 15p, Aug. 2015. | pt_BR |
| ISSN | 1664-3224 | |
| URI | https://www.arca.fiocruz.br/handle/icict/12771 | |
| Language | eng | pt_BR |
| Publisher | Frontiers Media | pt_BR |
| Rights | open access | |
| Title | A tale from TGF-β superfamily for thymus ontogeny and function | pt_BR |
| Type | Article | |
| DOI | 10.3389/fimmu.2015.00442 | |
| Abstract | Multiple signaling pathways control every aspect of cell behavior, organ formation, and
tissue homeostasis throughout the lifespan of any individual. This review takes an ontogenetic
view focused on the large superfamily of TGF-β/bone morphogenetic protein
ligands to address thymus morphogenesis and function in T cell differentiation. Recent
findings on a role of GDF11 for reversing aging-related phenotypes are also discussed. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Ciências Biomédicas. Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | TGF-β | pt_BR |
| Subject | BMP | pt_BR |
| Subject | Thymus | pt_BR |
| Subject | Thymopoiesis | pt_BR |
| Subject | T cell development | pt_BR |
| DeCS | Timo | pt_BR |
