Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/13095
Title: Clinical conditions associated with intestinal strongyloidiasis in Rio de Janeiro, Brazil
Authors: Cabral, Anna Caryna
Iñiguez, Alena Mayo
Moreno, Taiza
Bóia, Marcio Neves
Costa, Filipe Anibal Carvalho
Affilliation: Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Disciplina de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Epidemiologia e Sistemática Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.
Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Disciplina de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Epidemiologia e Sistemática Molecular. Rio de Janeiro, RJ, Brasil.
Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Disciplina de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Epidemiologia e Sistemática Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Escritório Regional. Teresina, PI, Brasil.
Abstract: Introduction: Strongyloides stercoralis is a soil-transmitted helminth that produces an infection that can persist for decades. The relationships between certain clinical conditions and strongyloidiasis remains controversial. This study aims to identify the clinical conditions associated with intestinal strongyloidiasis at a reference center for infectious diseases in Rio de Janeiro, Brazil. Methods: The clinical conditions that were assessed included HIV/AIDS, HTLV infection, cardiovascular diseases, diabetes, obstructive respiratory diseases, viral hepatitis, tuberculosis, cancer, chronic renal disease, nutritional/metabolic disorders, psychiatric conditions, rheumatic diseases and dermatologic diseases. We compared 167 S. stercoralis-positive and 133 S. stercoralis-negative patients. Results: After controlling for sex (male/female OR = 2.29; 95% (CI): (1.42 - 3.70), rheumatic diseases remained signifi cantly associated with intestinal strongyloidiasis (OR: 4.96; 95% CI: 1.34-18.37) in a multiple logistic regression model. With respect to leukocyte counts, patients with strongyloidiasis presented with signifi cantly higher relative eosinophil (10.32% ± 7.2 vs. 4.23% ± 2.92) and monocyte (8.49% ± 7.25 vs. 5.39% ± 4.31) counts and lower segmented neutrophil (52.85% ± 15.31 vs. 61.32% ± 11.4) and lymphocyte counts (28.11% ± 9.72 vs. 30.90% ± 9.51) than S. stercoralis-negative patients. Conclusions: Strongyloidiasis should be routinely investigated in hospitalized patients with complex conditions facilitate the treatment of patients who will undergo immunosuppressive therapy. Diagnoses should be determined through the use of appropriate parasitological methods, such as the Baermann-Moraes technique.
Keywords: Strongyloides stercoralis
Co-infection
Risk Factors
DeCS: Strongyloides stercoralis
Fatores de Risco
Issue Date: 2015
Publisher: Sociedade Brasileira de Medicina Tropical
Citation: CABRAL, Anna Caryna; et al. Clinical conditions associated withintestinal strongyloidiasis in Rio de Janeiro, Brazil. Rev. Soc. Bras. Med. Trop., v.48, n.3, p.321-325, May-June 2015.
DOI: 10.1590/0037-8682-0019-2015
ISSN: 1678-9849
Copyright: open access
Appears in Collections:PI - Artigos de Periódicos
IOC - Artigos de Periódicos

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