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Title: | First report of autochthonous transmission of Zika virus in Brazil |
Authors: | Zanluca, Camila Melo, Vanessa Campos Andrade de Mosimann, Ana Luiza Pamplona Santos, Glauco Igor Viana dos Santos, Claudia Nunes Duarte dos Luz, Kleber Giovanni |
Affilliation: | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil. Secretaria Estadual de Saúde do Rio Grande do Norte. Natal, RN, Brasil. Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil. Secretaria Estadual de Saúde do Rio Grande do Norte. Natal, RN, Brasil. Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil. Universidade Federal do Rio Grande do Norte. Instituto de Medicina Tropical. Natal, RN, Brasil. |
Abstract: | In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil. |
Keywords: | Zika Virus Dengue Aedes aegypti |
keywords: | Vírus Zika Dengue Aedes aegypti Brasil |
DeCS: | Aedes Dengue |
Issue Date: | 2015 |
Citation: | ZANLUCA Camila; MELO, Vanessa Campos Andrade de; MOSIMANN, Ana Luiza Pamplona; SANTOS, Glauco Igor Viana dos; SANTOS, Claudia Nunes Duarte dos; LUZ, Kleber. First report of autochthonous transmission of Zika virus in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 110, n. 4, p. 569–572, June. 2015. |
DOI: | 10.1590/0074-02760150192 |
ISSN: | 1678-8060 |
Copyright: | open access |
Appears in Collections: | PR - ICC - Artigos de Periódicos |
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