Author | Santoro, Ferrucio | |
Author | Sadigursky, Moysés | |
Author | Sherlock, Ítalo Rodrigues de Araújo | |
Author | Afchain, Daniel | |
Author | Capron, A. | |
Access date | 2016-03-31T17:50:50Z | |
Available date | 2016-03-31T17:50:50Z | |
Document date | 1987 | |
Citation | SANTORO, F. et al. Studies on anti-componenet 5 antibodies in animals infected with Trypanosoma cruzi. Revista da Sociedade Brasileira de Medicina Tropical, v. 20, n. 2, p. 91-94, 1987. | pt_BR |
ISSN | 0037-8682 | |
URI | https://www.arca.fiocruz.br/handle/icict/13428 | |
Language | eng | pt_BR |
Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
Rights | open access | pt_BR |
Title | Studies on anti-componenet 5 antibodies in animals infected with Trypanosoma cruzi | pt_BR |
Type | Article | pt_BR |
Abstract | A competitive antibody enzyme immunoassay, using a monoclonal antibody against
the species-specific Trypanosoma cruzi antigen 5, was used to investigate the presence o f
anti-component 5 antibodies in sera of opossums, dogs, rabbits and rats infected with this
parasite. The sera from 51 Venezuelan patients with Chagas’disease were also tested. About
90% of the infected subjects showed significant levels o f anti-component 5 antibodies.
Nevertheless, these antibodies were not detected in the sera o f dogs, rats and opossums
infected with T. cruzi. Some sera from infected rabbits presented significant results but
close to the limit o f positivity o f the test. Thesefindings suggest that the immune response
in animals naturally or experimentally infected with T. cruzi is different from that
observed in human Chagas’disease. | pt_BR |
Affilliation | Institut Pasteur. Centre d’Immunologie et de Biologie Parasitaire. (Unité Mixte INSERM). Lille Cédex, France | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Institut Pasteur. Centre d’Immunologie et de Biologie Parasitaire. (Unité Mixte INSERM). Lille Cédex, France | pt_BR |
Affilliation | Institut Pasteur. Centre d’Immunologie et de Biologie Parasitaire. (Unité Mixte INSERM). Lille Cédex, France | pt_BR |
Subject | Trypanosoma cruzi | pt_BR |
Subject | Antibodies | pt_BR |
Subject | Immunoassay | pt_BR |