Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/13665
Title: Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise
Authors: Sarno, Manoel
Sacramento, Gielson Almeida do
Khouri, Ricardo
Rosário, Mateus Santana do
Costa, Federico
Archanjo, Gracinda
Santos, Luciane Amorim
Nery Junior, Nivison
Vasilakis, Nikos
Ko, Albert Icksang
Almeida, Antonio R. P. de
Affilliation: Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil
Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut, USA
Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
The University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Pathology and Center of Biodefense and Emerging Infectious Diseases. Galveston, Texas, USA
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut, USA
Hospital Geral Roberto Santos, Secretaria Estadual da Saúde da Bahia., Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil
Abstract: The rapid spread of Zika virus in the Americas and outbreak of microcephaly in Brazil has raised attention to the possible deleterious effects that the virus may have on fetuses. We report a case of a 20-year-old pregnant woman from Salvador, Brazil whose fetus had developed hydrops fetalis, a condition where there is abnormal accumulation of fluid in the fetus, as well as severe central nervous system defects such as microcephaly and hydranencephaly. After fetal demise, ZIKV RNA was detected in central nervous system tissues and amniotic fluid. The case report provides evidence that in addition to microcephaly, there may be a link between Zika virus infection and hydrops fetalis and fetal demise. Given the recent spread of the virus, systematic investigation of spontaneous abortions and stillbirths may be warranted to evaluate the risk that ZIKV infection imparts on these outcomes.
keywords: Zika virus
Infecção
Hidrocefalia
Microcefalia
Americas
Brasil
Feminino
Gravidez
Feto
Hidropsia Fetal
Morte fetal
Sistema Nervoso Central
Aborto
Issue Date: 2016
Publisher: Public Library of Science
Citation: SARNO, M. et al. Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal demise. Plos Neglected Tropical Diseases, v. 10, n. 2, p. e0004517, 2016.
ISSN: 1935-2727
10.1371/journal.pntd.0004517
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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