Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/13967
Title: Zika virus: History, emergence, biology, and prospects for control
Authors: Weaver, Scott C
Costa, Federico
Blanco, Mariano A. Garcia
Ko, Albert Icksang
Ribeiro, Guilherme de Sousa
Saade, George
Shi, Pei-Yong
Vasilakis, Nikos
Affilliation: University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Microbiology & Immunology. Galveston TX, USA / University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Pathology. Galveston TX, USA
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto da Saúde Coletiva. Salvador, BA, Brasil
University of Texas Medical Branch. Department of Biochemistry & Molecular Biology. Galveston, TX, USA / Duke-NUS Medical School. Programme in Emerging Infectious Diseases. Singapore
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto da Saúde Coletiva. Salvador, BA, Brasil
University of Texas Medical Branch. Department of Obstetrics and Gynecology. Galveston, TX, USA
University of Texas Medical Branch. Department of Biochemistry & Molecular Biology, and Sealy Center for Structural Biology & Molecular Biophysics. Galveston, TX, USA / University of Texas Medical Branch. Department of Pharmacology & Toxicology, and Sealy Center for Structural Biology & Molecular Biophysics. Galveston, TX, USA
University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Microbiology & Immunology. Galveston TX, USA / University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Pathology. Galveston TX, USA
Abstract: Zika virus (ZIKV), a previously obscure flavivirus closely related to dengue, West Nile, Japanese encephalitis and yellow fever viruses, has emerged explosively since 2007 to cause a series of epidemics in Micronesia, the South Pacific, and most recently the Americas. After its putative evolution in sub-Saharan Africa, ZIKV spread in the distant past to Asia and has probably emerged on multiple occasions into urban transmission cycles involving Aedes (Stegomyia) spp. mosquitoes and human amplification hosts, accompanied by a relatively mild dengue-like illness. The unprecedented numbers of people infected during recent outbreaks in the South Pacific and the Americas may have resulted in enough ZIKV infections to notice relatively rare congenital microcephaly and GuillaineBarr e syndromes. Another hypothesis is that phenotypic changes in Asian lineage ZIKV strains led to these disease outcomes. Here, we review potential strategies to control the ongoing outbreak through vector-centric approaches as well as the prospects for the development of vaccines and therapeutics
keywords: Zika virus
Dengue
Epidemia
Transmissão
Mosquitos
Microcefalia
Surto de doenças
Vacinas
História
Controle
Situação de emergência
Issue Date: 2016
Publisher: Elsevier Masson
Citation: WEAVER, S. C. et al. Zika virus: History, emergence, biology, and prospects for control. Antiviral Research, v. 130, p. 69e80, 2016.
DOI: dx.doi.org/10.1016/j.antiviral.2016.03.010
ISSN: 0166-3542
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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