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THE MITOGENOME OF ONCHOCERCA VOLVULUS FROM THE BRAZILIAN AMAZONIA FOCUS
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Abstract
We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa.
An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of highthroughput
and Sanger sequencing technologies. Comparisons made between this mitochondrial genome and
publicly available mitochondrial sequences identified 46 variant nucleotide positions and suggested that our
Brazilian mitogenome is more closely related to Cameroon-origin mitochondria than West African-origin mitochondria.
As well as providing insights into the origins of Latin American onchocerciasis, the Brazilian Amazonia
focus mitogenome may also have value as an epidemiological resource.
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