From Mosquitos to Humans: Genetic Evolution of Zika Virus

University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA / Chinese Academy of Medical Sciences & Peking Union Medical College. Institute of Basic Medical Sciences. Center for Systems Medicine. Beijing, China / Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.
University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA / David Geffen School of Medicine at UCLA. Department of Obstetrics & Gynecology. Los Angeles, CA, USA.
Chinese Academy of Medical Sciences & Peking Union Medical College. Institute of Basic Medical Sciences. Center for Systems Medicine. Beijing, China / Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.
University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA / Chinese Academy of Sciences. Institute of Biophysics. Beijing 100101, China.
University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratorio Biologia Molecular de Flavivírus. Rio de Janeiro, RJ, Brasil.
University of California. 8UCLA Center for World Health,. Los Angeles, CA, USA.
David Geffen School of Medicine at UCLA. Division of Pediatric Infectious Diseases. Los Angeles, CA, USA.
Chinese Academy of Medical Sciences & Peking Union Medical College. Institute of Basic Medical Sciences. Center for Systems Medicine. Beijing, China / Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.
University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA .
University of California. Department of Microbiology, Immunology and Molecular Genetics. Los Angeles, CA, USA / Chinese Academy of Medical Sciences & Peking Union Medical College. Institute of Basic Medical Sciences. Center for Systems Medicine. Beijing, China / Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.

Abstract

Initially isolated in 1947, Zika virus (ZIKV) has recently emerged as a significant public health concern. Sequence analysis of all 41 known ZIKV RNA open reading frames to date indicates that ZIKV has undergone significant changes in both protein and nucleotide sequences during the past half century.

Keywords

Zika Virus
Flavivirus
Sequence analysis
41 known ZIKV RNA
Nucleotide sequences

DeCS

Zika Virus
Flavivirus
Análise de Sequência
Sequência de Bases

Publisher

Elsevier

Later version

https://www.arca.fiocruz.br/handle/icict/16518

Citation

WANG, Lulan; et al. From Mosquitos to Humans: Genetic Evolution of Zika Virus. Cell Host & Microbe, v. 19, n. 5, p. 561-565, May 2016.

DOI

10.1016/j.chom.2016.04.006

ISSN

1931-3128

Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/14682

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Open access

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