Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/14683
Title: Characterization of two isolates of Trypanosoma cruzi obtained from the patient Berenice, the first human case of Chagas’ disease described by Carlos Chagas in 1909
Authors: Lana, Marta de
Chiari, Clea A.
Chiari, Egler
Morel, Carlos Medicis
Gonçalves, Antonio M.
Romanha, Álvaro J.
Affilliation: Universidade Federal de Ouro Preto. Escola de Farmácia. Departamento de Análises Clínicas. Ouro Preto, MG, Brasil.
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Parasitologia. Belo Horizonte, MG, Brasil.
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Parasitologia. Belo Horizonte, MG, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Parasitologia Celular e Molecular. Belo Horizonte, MG, Brasil.
Abstract: Two isolates of Trypanosoma cruzi were obtained from the patient Berenice, the first human case of Chagas’ disease (Chagas 1909), when she was 55 and 71 years old, respectively. The isolates were characterized on the basis of their epimastigote-trypomastigote differentiation in liquid media and of the electrophoretic pattern of EcoR1 digestion products of kinetoplast DNA (kDNA) minicircles (schizodeme) and isoenzyme patterns (zymodeme). Clear differences were found between the isolates, suggesting the occurrence of a heterogeneous population of T. cruzi in the infection of this patient.
Keywords: Trypanosoma cruzi
Chagas`Disease
Brazil
History
keywords: História
DeCS: Trypanosoma cruzi
Doença de Chagas
Issue Date: 1996
Publisher: Springer Verlag
Citation: LANA, M. de; et al. Characterization of two isolates of Trypanosoma cruzi obtained from the patient Berenice, the first human case of Chagas’ disease described by Carlos Chagas in 1909. Parasitology Research, v. 82, n. 3, p. 257-260, 1996.
DOI: 10.1007/s004360050106
ISSN: 0932-0113
Copyright: open access
Appears in Collections:MG - IRR - Artigos de Periódicos
IOC - Artigos de Periódicos

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